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Graduating School 【 display / non-display 】
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Hokkaido University Faculty of Agriculture 応用生命科学科 Graduated
Graduate School 【 display / non-display 】
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Hokkaido University 農学研究科 農芸化学専攻 Master's Course Completed
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Nagoya University 生命農学研究科 生物機構・機能科学専攻 Doctor's Course Completed
Degree 【 display / non-display 】
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Hokkaido University - 学士（農学）
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Hokkaido University - 修士（農学）
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Nagoya University - 博士（農学）
Academic Society Affiliations 【 display / non-display 】
- 日本農芸化学会
- 糸状菌分子生物学研究会
- 日本ケミカルバイオロジー学会
Research field 【 display / non-display 】
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Life Science / Bioorganic chemistry
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Life Science / Applied microbiology
Papers 【 display / non-display 】
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Linkage-Editing Pseudo-Glycans: A Reductive α-Fluorovinyl-C-Glycosylation Strategy to Create Glycan Analogs with Altered Biological Activities
Takahiro Moriyama, Makoto Yoritate, Naoki Kato, Azusa Saika, Wakana Kusuhara, Shunsuke Ono, Takahiro Nagatake, Hiroyuki Koshino, Noriaki Kiya, Natsuho Moritsuka, Riko Tanabe, Yu Hidaka, Kazuteru Usui, Suzuka Chiba, Noyuri Kudo, Rintaro Nakahashi, Kazunobu Igawa, Hiroaki Matoba, Katsuhiko Tomooka, Eri Ishikawa, Shunji Takahashi, Jun Kunisawa, Sho Yamasaki, Go Hirai
Journal of the American Chemical Society146 ( 3 ) 2237 - 2247 2024.01
Joint Work
Research paper (scientific journal)
Authorship: Corresponding author
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cis-Decalin-containing tetramic acids as inhibitors of insect steroidogenic glutathione S-transferase Noppera-bo
Naoki Kato, Kana Ebihara, Toshihiko Nogawa, Yushi Futamura, Kazue Inaba, Akiko Okano, Harumi Aono, Yuuta Fujikawa, Hideshi Inoue, Kazuhiko Matsuda, Hiroyuki Osada, Ryusuke Niwa, Shunji Takahashi
PLOS ONE18 e0290851 2023.08
Joint Work
Research paper (scientific journal)
Authorship: Lead author Corresponding author
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Molecular Basis for Two Stereoselective Diels–Alderases that Produce Decalin Skeletons.
Keisuke Fujiyama, Naoki Kato, Suyong Re, Kiyomi Kinugasa, Kohei Watanabe, Ryo Takita, Toshihiko Nogawa, Tomoya Hino, Hiroyuki Osada, Yuji Sugita, Shunji Takahashi, Shingo Nagano
Angewandte Chemie International Edition60 ( 41 ) 22401 - 22410 2021.06
Joint Work
Research paper (scientific journal)
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Control of the stereochemical course of [4+2] cycloaddition during trans-decalin formation by Fsa2-family enzymes.
Kato N, Nogawa T, Takita R, Kinugasa K, Kanai M, Uchiyama M, Osada H, Takahashi S
Angew Chem Int Ed Engl 2018.07
Joint Work
Research paper (scientific journal)
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Elucidation of the stereocontrol mechanisms of the chemical and biosynthetic intramolecular Diels–Alder cycloaddition for the formation of bioactive decalins
Takumi Kariya, Hayato Hasegawa, Taro Udagawa, Yusaku Inada, Kyoko Nishiyama, Mieko Tsuji, Tasuku Hirayama, Tatsuo Suzutani, Naoki Kato, Shingo Nagano, Hideko Nagasawa
RSC Advances13 27828 - 27838 2023.09
Joint Work
Research paper (scientific journal)
Review Papers 【 display / non-display 】
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Diels-Alderaseの謎に挑む～鏡像異性体をつくり分けるしくみ
加藤 直樹，藤山 敬介，永野 真吾
月刊化学 ( 化学同人 ) 77 ( 4 ) 70 - 71 2022.04
Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media) Joint Work
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麹菌においてマイコトキシン生産を防ぐセーフガードとシクロピアゾン酸生合成機構
加藤直樹，徳岡昌文，篠原靖智，小山泰二，長田裕之
JSM Mycotoxins 2014.09
Article, review, commentary, editorial, etc. (scientific journal) Joint Work
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麹菌の二次代謝産物研究の新展開
徳岡昌文，加藤直樹
日本醸造協会誌 2013.09
Article, review, commentary, editorial, etc. (scientific journal) Joint Work
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Construction of a microbial natural product library for chemical biology studies.
Kato N, Takahashi S, Nogawa T, Saito T, Osada H
Curr. Opin. Chem. Biol. 2012.04
Article, review, commentary, editorial, etc. (scientific journal) Joint Work
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天然化合物ライブラリーの構築と利用
斎藤臣雄，野川俊彦，加藤直樹，近藤恭光，長田裕之
蛋白質核酸酵素 2009.09
Article, review, commentary, editorial, etc. (scientific journal) Joint Work
Presentations 【 display / non-display 】
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Establishment of natural product screening system using biosynthetic enzyme inhibitor
JSBBA 2024 Annual Meeting 東京農業大学 Japan Domestic presentation Oral presentation (general)
2024.03Announcement date:2024.03.26
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Difference in the amylase induction by sugar analogues in Aspergilli
JSBBA 2024 Annual Meeting 東京農業大学 Japan Domestic presentation Oral presentation (general)
2024.03Announcement date:2024.03.27
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Structure-activity relationship of decalin-containing tetramic acids collected from genetically engineered fungi
5th KRIBB-RIKEN Chemical Biology Joint Symposium Ochang Branch Institute, KRIBB Korea, Republic of International presentation Oral presentation (invited, special)
2023.10Announcement date:2023.10.17
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Structure-activity relationship of decalin-containing tetramic acids collected from genetically engineered fungi
日本農芸化学会2023年度大会 オンライン Domestic presentation Oral presentation (general)
2023.03 -
微生物の二次代謝研究～「どうやって」「なぜ」作るのかの理解を目指して～
29th Setsudai Agricultural Seminar オンライン Domestic presentation Public lecture, seminar, tutorial, course, or other speech
2022.06
Awards 【 display / non-display 】
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2021年度長瀬研究振興賞
公益財団法人 長瀬科学技術振興財団 Award from publisher, newspaper, foundation, etc.
Country:Japan
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2019年度理研梅峰賞
理化学研究所 Other
Country:Japan
Research Grants and Projects 【 display / non-display 】
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切れない糖アナログを⽤いた微⽣物の多糖分解酵素⽣産制御系の解明
2024.04 - 2026.03
Institute for Fermentation 2024年度一般研究助成
Authorship：Principal investigator Grant type：Competitive
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ジアステレオ選択的酵素の合理的改変による天然化合物の骨格多様性拡張
2023.04 - 2026.03
日本学術振興会 科研費 基盤研究（B）
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ニコチン性アセチルコリン受容体のダイナミズムの解明に基づく昆虫制御の先端開拓
2021.04 - 2024.03
日本学術振興会 科研費 基盤研究（A）
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⽴体選択的Diels-Alder反応を触媒する酵素の機能改変による⾮天然型機能性分⼦の創製
2021.04 - 2022.03
⻑瀬科学技術振興財団 ⻑瀬科学技術振興財団 研究助成
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モデル系統を用いた菌類におけるストリゴラクトン応答機構の解明
2020.04 - 2025.03
日本学術振興会 科研費 挑戦的研究（開拓）