|
Job title |
Professor |
Research Interests 【 display / non-display 】
-
Computer Chemistry
-
Medicinal Chemistry
Graduating School 【 display / non-display 】
-
Hokkaido University Faculty of Science Graduated
Graduate School 【 display / non-display 】
-
Hokkaido University Graduate School, Division of Natural Science Master's Course Completed
Degree 【 display / non-display 】
-
Hokkaido University - 修士（理学）
-
Toyohashi University of Technology - 博士（工学）
Academic Society Affiliations 【 display / non-display 】
- 日本薬学会
- CBI学会
- American Chemical Society
Research field 【 display / non-display 】
-
Life Science / Pharmaceutical chemistry and drug development sciences (医薬品化学 計算化学)
Papers 【 display / non-display 】
-
Electrophilic aromatic substitution using fluorinated isoxazolines at C5 position via C-F bond cleavage
Kazuyuki Sato, Tomohiro Kuroki, Haruka Minami, Azusa Sato, Yukiko Karuo, Atsushi Tarui, Kentaro Kawai, Masaaki Omote
RSC Advances2024 ( 14 ) 39543 - 39549 2024.12
Joint Work
Research paper (scientific journal)
-
Synthesis of fluoroalkenes and fluoroenynes via cross-coupling reactions using novel multihalogenated vinyl ethers
Yukiko Karuo, Keita Hirata, Atsushi Tarui, Kazuyuki Sato, Kentaro Kawai, Masaaki Omote
Beilstein J. Org. Chem.2024 ( 20 ) 2691 - 2703 2024.10
Joint Work
Research paper (scientific journal)
-
Development of drug discovery platforms using artificial intelligence and cheminformatics
Kentaro Kawai, Yukiko Karuo, Atsushi Tarui, Kazuyuki Sato, Makoto Kataoka, Masaaki Omote
Chem. Pharm. Bull.2024 ( 72 ) 794 - 799 2024.09
Joint Work
Research paper (scientific journal)
Authorship: Lead author Corresponding author
-
Construction of new quaternary carbon center of fluorinated isoxazolines at C5 position via C-F bond cleavage
Kazuyuki Sato, Kazuki Nakano, Takahiro Ueda, Yukine Kitamura, Yuna Tanaka, Yukiko Karuo, Atsushi Tarui, Kentaro Kawai, Masaaki Omote
Journal of Fluorine Chemistry279 110335 - 110335 2024.08
Joint Work
Research paper (scientific journal)
-
Advancements and challenges of artificial intelligence in drug discovery and synthetic organic chemistry
Kentaro Kawai
The Journal of Synthetic Organic Chemistry82 ( 8 ) 780 - 790 2024.08
Single Work
Research paper (scientific journal)
Authorship: Lead author Last author Corresponding author
Books 【 display / non-display 】
-
SHIN薬学 医薬品化学と病態生理が深める８大疾患への機序と治療の理解
表雅章、倉本展行、小森浩二、石丸侑希、軽尾友紀子、河合健太郎、佐藤和之、田中雅幸、辻琢己、向井啓、米山雅紀Textbook, survey, introduction Joint author
京都廣川書店 2024.03
-
Optimisation of data collection and analysis methods in chemoinformatics.
Kentaro KawaiScholarly book Joint author
Technical Information Institute Co.,Ltd. 2023.04
-
in silico創薬におけるスクリーニングの高速化・高精度化技術
河合健太郎, 山野辺進、服部一成、嶋田朋嘉 (Part : 製薬企業からみた, 創薬へのスーパーコンピューターの応用のポイント) Scholarly book Contributor
技術情報協会 2018.01
Review Papers 【 display / non-display 】
-
SVMを用いた薬物多重活性クラスの分類学習と予測
高橋 由雅, 河合 健太郎
生物工学会誌 ( 日本生物工学会 ) 86 ( 12 ) 589 - 592 2008.12
Article, review, commentary, editorial, etc. (scientific journal) Joint Work
Presentations 【 display / non-display 】
-
Proposal of new docking pose descriptor LCP2 and comparison of prediction performances
The 145th Annual Meeting of the Pharmaceutical Society of Japan Domestic presentation Poster presentation
2025.03 -
Synthesis of azole derivatives for the discovery of novel pharmacokinetic boosters
The 145th Annual Meeting of the Pharmaceutical Society of Japan Domestic presentation Poster presentation
2025.03 -
Design, synthesis and biological activity of novel aminoethylphenol derivatives as ceramide equivalents
The 145th Annual Meeting of the Pharmaceutical Society of Japan Domestic presentation Poster presentation
2025.03 -
Synthesis of piperidine derivatives as bacterial MATE-type drug efflux transporter inhibitors
The 145th Annual Meeting of the Pharmaceutical Society of Japan Domestic presentation Poster presentation
2025.03 -
Intramolecular radical cyclization using 1,1-difluoroethoxyaryl
The 145th Annual Meeting of the Pharmaceutical Society of Japan Domestic presentation Oral presentation (general)
2025.03