Papers - OYAMA Hiroshi

Dipeptidyl aminopeptidase IV from Stenotrophomonas maltophilia exhibits activity against a substrate containing a 4-hydroxyproline residue.

中嶋義隆、伊藤潔、十島翼、永川貴、Ｚｈｅｎｇ，Ｈ．、Ｗｕ，ＹＦ．、高橋栄二、京野潔、芳本忠

Ｊｏｕｒｎａｌ　ｏｆ　Ｂａｃｔｅｒｉｏｌｏｇｙ190 ( 23 ) 7819 - 7829   2008.09

Joint Work

Novel inhibitor for prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis and details of substrate-recognition mechanism.

Ｘｕ，Ｙ．、中嶋義隆、伊藤潔、Ｚｈｅｎｇ，Ｈ．、Ｈｅｉｓｅｒ，Ｕ．、Ｈｏｆｆｍａｎｎ，Ｔ．、Ｇａｒｔｎｅｒ，ＵＴ．、Ｄｅｍｕｔｈ，ＨＵ．、芳本忠

Ｊｏｕｒｎａｌ　ｏｆ　Ｍｏｌｅｃｕｌａｒ　Ｂｉｏｌｏｇｙ375 ( 3 ) 708 - 719   2008.01

Joint Work

Oligonucleotide transformation for the study of mutagenic specificities of DNA lesions in yeast.

根岸和雄、関根大二郎、森光巧、鈴木哲夫、奥川洋司、川上朝子、大塚智恵、Ｌｏａｋｅｓ，Ｄ．　

Ｎｕｃｌｅｉｃ　Ａｃｉｄｓ　Ｓｙｍｐ　Ｓｅｒ　（Ｏｘｆ）51 ( 1 ) 211 - 212   2007.11

Joint Work

Processing, catalytic activity and crystal structures of kumamolisin-As with an engineered active site.

大久保安由美、Ｌｉ，Ｍ．、芦田理子、Ｇｕｓｔｃｈｉｎａ，Ａ．、小田耕平、Ｄｕｎｎ，ＢＭ．、Ｗｌｏｄａｗｅｒ，Ａ．、中山亨

ＦＥＢＳ　Ｊ．273 ( 11 ) 2563 - 2576   2006.06

Joint Work

Synergetic effects of pressure and chemical denaturant on protein unfolding: stability of a serine-type carboxyl protease, kumamolisin.

藤本泰範、池内秀和、多田朋子、小田耕平、功刀滋

Ｂｉｏｃｈｉｍ．Ｂｉｏｐｈｙｓ．Ａｃｔａ1764 ( 3 ) 364 - 371   2006.03

Joint Work

Molecular cloning of the gene encoding Vibrio metalloproteinase vimelysin and isolation of a mutant with high stability in organic solvents.

高橋敏宏、Ｎｇ，ＫＫ．、小田耕平

Ｊｏｕｒｎａｌ　ｏｆ　Ｂｉｏｃｈｅｍｉｓｔｒｙ　（Ｔｏｋｙｏ）138 ( 6 ) 701 - 710   2005.12

Joint Work

Purification and characterisation of keratinase from a thermotolerant feather-degrading bacterium.

Suntornsuk,W.,Tongjun,J.,Onnim,P.,Ratanakanokchai,K.,Kusamran,T.,小田耕平

Ｗｏｒｌｄ　Ｊ．Ｍｉｃｒｏｂｉｏｌ．Ｂｉｏｔｅｃｈ．21 ( 40701 ) 1111 - 1117   2005.10

Joint Work

Catalytic residues and substrate specificity of recombinant human tripeptidyl peptidase I (CLN2).

藤澤智子、鈴木健夫、Ｗｌｏｄａｗｅｒ，Ａ．、Ｄｕｎｎ，ＢＭ．、小田耕平

Ｊｏｕｒｎａｌ　ｏｆ　Ｂｉｏｃｈｅｍｉｓｔｒｙ　（Ｔｏｋｙｏ）138 ( 2 ) 127 - 134   2005.08

Joint Work

Catalytic residues and substrate specificity of scytalidoglutamic peptidase, the first member of theeqolisin in family (G1) of peptidases.

片岡由起子、高田克巳、常見雅彦、Ｊａｍｅｓ，ＭＮ．、小田耕平

ＦＥＢＳ　Ｌｅｔｔ．579 ( 14 ) 3364 - 3369   2005.06

Joint Work

Crystallographic and biochemical investigations of kumamolisin-As, a serine-carboxyl peptidase with collagenase activity.

Wlodawer,A.,Li,M.,Gustchina,A.,鶴岡直樹,芦田理子,南方宏之,小田耕平,西野徳三,中山亨

Ｊ．Ｂｉｏｌ．Ｃｈｅｍ．279 ( 20 ) 21500 - 21510   2004.10

Joint Work

1.2 A crystal structure of the serine carboxyl proteinase pro-kumamolisin: structure of an intact pro-subtilase.

Comellas-Bigler,M.,Maskos,K.,Huber,R.,小田耕平,Bode,W.

Ｓｔｒｕｃｔｕｒｅ（Ｃａｍｂ）12 ( 7 ) 1313 - 1323   2004.07

Joint Work

Two inhibitor molecules bound in the active site of Pseudomonas sedolisin: a model for the bi-product complex following cleavage of a peptide substrate.

Wlodawer,A.,Li,M.,Gustchina,A.,小田耕平,Beyer,BB.,Clemente,J.,Dunn,BM.

Ｂｉｏｃｈｅｍ．Ｂｉｏｐｈｙｓ　Ｒｅｓ．Ｃｏｍｍｕｎ．314 ( 2 ) 3364 - 3369   2004.06

Joint Work

The molecular structure and catalytic mechanism of a novel carboxyl peptidase from Scytalidium lignicolum.

Fujinaga,M.,Cherney,MM.,小田耕平,James,MN.

Ｐｒｏｃ．Ｎａｔｌ．Ａｃａｄ．Ｓｃｉ．ＵＳＡ．101 ( 10 ) 3364 - 3369   2004.05

Joint Work

Purification and characterization of alkaline serine proteinase from photosynthetic bacterium,Rubrivivax gelatinosus KDDS1

小田耕平、Ｔａｎｓｋｕｌ，Ｓ．、Ｎｏｐａｒａｔｎａｒａｐｏｒｎ，Ｎ．　

Ｂｉｏｓｃｉｅｎｃｅ，Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ68 ( 3 ) 650 - 655   2004.03

Joint Work

Substrate specificity of alkaline serine proteinase isolated from photosynthetic bacterium,Rubrivivax gelatinosus KDDS1.

Tanskul,S.,小田耕平,Noparatnaraporn,N.,常見雅彦,高田克巳

Ｂｉｏｃｈｅｍ．Ｂｉｏｐｈｙｓ　Ｒｅｓ．Ｃｏｍｍｕｎ．309 ( 3 ) 547 - 551   2003.03

Joint Work

A model of tripeptidyl-peptidase I(CLN2), a ubiquitous and highly conserved member of the sedolisin family of serine-carboxyl peptidases.

Wlodawer,A.,Durell,SR.,Li,M.,小田耕平,Dunn,BM.

ＢＭＣ　Ｓｔｒｕｃｔ．Ｂｉｏｌ． ( 40610 )   2003.03

Joint Work

Collagenolytic serine-carboxyl proteinase from Alicyclobacillus sendaiensis strain NTAP-1:purification,characterization,gene cloning,and heterologous expression.

鶴岡直樹、中山亨、芦田理子、邊見久、中尾正宏、南方宏之、小田耕平、西野徳三

Ａｐｐｌｉｅｄ　ａｎｄ　Ｅｎｖｉｒｏｎｍｅｎｔａｌ　Ｍｉｃｒｏｂｉｏｌｏｇｙ69 ( 1 ) 162 - 169   2003.01

Joint Work

The 1.4 A crystal structure of kumamolysin:A thermostable serine-carboxy-type proteinase.

Comellas-Bigler,M.,Fuentes-Prior,P.,Maskos,K.,Huber,R.,内田健一,Dunn,BM.,小田耕平,Bode,W.

Ｓｔｒｕｃｔｕｒｅ（Ｃａｍｂ）10   865 - 876   2002.06

Joint Work

A CLN2-related and thermostable serine-carboxyl proteinase,kumamolysin:cloning,expression,and identification of catalytic serine residue.

浜田貴俊、小笠原心、内田健一、村尾澤夫、Ｂｅｙｅｒ，ＢＢ．、Ｄｕｎｎ，ＢＭ．、小田耕平

Ｊｏｕｒｎａｌ　ｏｆ　Ｂｉｏｃｈｅｍｉｓｔｒｙ（Ｔｏｋｙｏ）131 ( 5 ) 757 - 765   2002.05

Joint Work

Inhibitor complexes of the Pseudomonas serine-carboxyl proteinase.

Wlodawer,A.,Li,M.,Gustchina,A.,Dauter,Z.,内田健一,Goldfarb,NE.,Dunn,BM.,小田耕平

Ｂｉｏｃｈｅｍｉｓｔｒｙ40 ( 51 ) 15602 - 15611   2001.12

Joint Work