Papers - OMOTE Masaaki
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Decarboxylative aldol reaction of alpha,alpha-difluoro-beta-keto esters: easy access to difluoroenolate
Atsushi Tarui, Hiroshi Shimomura, Yohei Yasuno, Yukiko Karuo, Kazuyuki Sato, Kentaro Kawai, Masaaki Omote
ACS Omega9 ( 24 ) 26275 2025.06
Joint Work
Research paper (scientific journal)
Authorship: Corresponding author
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Electrophilic aromatic substitution using fluorinated isoxazolines at C5 position via C-F bond cleavage
Kazuyuki Sato, Tomohiro Kuroki, Haruka Minami, Azusa Sato, Yukiko Karuo, Atsushi Tarui, Kentaro Kawai, Masaaki Omote
RSC Advances14 39543 - 39549 2024.12
Joint Work
Research paper (scientific journal)
Authorship: Corresponding author
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Construction of new quaternary carbon center of fluorinated isoxazolines at C5 position via C-F bond cleavage
Kazuyuki Sato, Kazuki Nakano, Takahiro Ueda, Yukine Kitamura, Yuna Tanaka, Yukiko Karuo, Atsushi Tarui, Kentaro Kawai, Masaaki Omote
Journal of Fluorine Chemistry279 110335 2024.09
Joint Work
Research paper (scientific journal)
Authorship: Corresponding author
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Development of drug discovery platforms using artificial intelligence and cheminformatics
Kentaro Kawai, Yukiko Karuo, Atsushi Tarui, Kazuyuki Sato, Makoto Kataoka, Masaaki Omote
Chem. Pharm. Bull.72 ( 9 ) 794 - 799 2024.09
Joint Work
Research paper (scientific journal)
Authorship: Last author
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Synthesis of fluoroalkenes and fluoroenynes via cross-coupling reactions using novel multihalogenated vinyl ethers
Yukiko Karuo, Keita Hirata, Atsushi Tarui, Kazuyuki Sato, Kentaro Kawai, Masaaki Omote
Beilstein J. Org. Chem.20 2691 - 2703 2024.08
Joint Work
Research paper (scientific journal)
Authorship: Corresponding author
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Rhodium-catalyzed homo-coupling reaction of aryl Grignard reagents and its application for the synthesis of an integrin inhibitor
Kazuyuki Sato, Satoki Teranishi, Atsushi Sakaue, Yukiko Karuo, Atsushi Tarui, Kentaro Kawai, Hiroyuki Takeda, Tatsuo Kinashi, Masaaki Omote
Beilstein J. Org. Chem.20 1341 - 1347 2024.06
Joint Work
Research paper (scientific journal)
Authorship: Corresponding author
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In vitro demonstration of antedrug mechanism of a pharmacokinetic booster to improve CYP3A4 substrates by CYP3A4-mediated metabolism inhibition
Makoto Kataoka, Takenaka, Shota Fujii, Takato Masada, Keiko Minami, Toshihide Takagi, Masaaki Omote, Kentaro Kawai, Shinji Yamashita
Drug Metabolism and Pharmacokinetics56 101005 2024.04
Joint Work
Research paper (scientific journal)
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Pentafluorosulfanyl-substituted biaryl derivatives as MATE-type transporter inhibitors targeting drug-resistant bacteria International coauthorship
Susumu Shinya, Kentaro Kawai, Naoki Kobayashi, Yukiko Karuo, Atsushi Tarui, Kazuyuki Sato, Masato Otsuka, Masaaki Omote
Bioorganic & Medicinal Chemistry99 117606 2024.02
Joint Work
Research paper (scientific journal)
Authorship: Last author
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Metal-Free Arylation of Pyridine/Quinoline N-Oxides with Indoles International coauthorship
Ryo Tsunokawa, Yukiko Karuo, Atsushi Tarui, Kazuyuki Sato, Takaaki Hosoya, Tomohiro Agou, Kentaro Kawai, Masaaki Omote
European Journal of Organic Chemistry26 ( 47 ) e20230 2023.11
Joint Work
Research paper (scientific journal)
Authorship: Corresponding author
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Reactions using freons and halothane as halofluoroalkyl/halofluoroalkenyl building blocks
Yukiko Karuo, Atsushi Tarui, Kazuyuki Sato, Kentaro Kawai, Masaaki Omote
The Chemical Record e202300029 2023.04
Joint Work
Research paper (scientific journal)
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Rhodium-catalyzed intramolecular reductive aldol-type cyclization: Application for the synthesis of a chiral necic acid lactone
Motoyuki Isoda, Kazuyuki Sato, Kenta Kameda, Kana Wakabayashi, Ryota Sato, Hideki Minami, Yukiko Karuo, Atsushi Tarui, Kentaro Kawai, Masaaki Omote
Beilstein J. Org. Chem.18 1642 - 1648 2022.11
Joint Work
Research paper (scientific journal)
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Simple synthesis of multi-halogenated alkenes from 2-bromo-2-chloro-1,1,1-trifluoroethane (halothane)
Yukiko Karuo, Atsushi Tarui, Kazuyuki Sato, Kentaro Kawai, Masaaki Omote
Beilstein J. Org. Chem.18 1567 - 1574 2022.11
Joint Work
Research paper (scientific journal)
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Fluorophenylalkyl-Substituted Cyanoguanidine Derivatives as Bacteria-Selective MATE Transporter Inhibitors for the Treatment of Antibiotic-Resistant Infections
Susumu Shinya, Kentaro Kawai, Naoki Kobayashi, Yukiko Karuo, Atsushi Tarui, Kazuyuki Sato, Masato Otsuka, Masaaki Omote
Bioorg. Med. Chem.74 117042 2022.09
Joint Work
Research paper (scientific journal)
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Discovery of benzyloxyphenyl- and phenethylphenyl-imidazole derivatives as a new class of ante–drug type boosters
Kentaro Kawai, Jun Okada, Mizuki Nakae, Toshiki Tsujimura, Yukiko Karuo, Atsushi Tarui, Kazuyuki Sato, Shinji Yamashita, Makoto Kataoka, Masaaki Omote
Bioorganic & Medicinal Chemistry Letters72 ( 15 ) 128868 2022.06
Joint Work
Research paper (scientific journal)
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Synthesis of 2,2-difluoro-2-arylethylamines as fluorinated analogues of octopamine and noradrenaline
Atsushi Tarui, Erika Kamata, Koji Ebisu, Yui Kawai, Ryota Araki, Takeshi Yabe, Yukiko Karuo, Kazuyuki Sato, Kentaro Kawai, Masaaki Omote
Heterocyclic Communications28 26 - 34 2022.03
Joint Work
Research paper (scientific journal)
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LCP: Simple Representation of Docking Poses for Machine Learning: A Case Study on Xanthine Oxidase Inhibitors
Kentaro Kawai, Yoshitaka Asanuma, Toshiki Kato, Yukiko Karuo, Atsushi Tarui, Kazuyuki Sato, Masaaki Omote
Molecular Informatics40 2100245 2021.11
Joint Work
Research paper (scientific journal)
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Importance of the azole moiety of cimetidine derivatives for the inhibition of human multidrug and toxin extrusion transporter 1 (hMATE1)
Susumu Shinya, Kentaro Kawai, Atsushi Tarui, Yukiko Karuo, Kazuyuki Sato, Masaya Matsuda, Kazuyuki Kitatani, Naoki Kobayashi, Takeshi Nabe, Masato Otsuka, Masaaki Omote
Chemical and Pharmaceutical Bulletin69 ( 9 ) 905 - 912 2021.09
Joint Work
Research paper (scientific journal)
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Identification and Synthesis of DDI-6, a Quinolinol Analog Capable of Activating Both Caenorhabditis elegans and Mouse Spermatozoa
Yukiko Karuo, Riona Shiraki, Ayaka Yoshida, Ryo Tsunokawa, Mayuko Nakahara-Yamada, Atsushi Tarui, Kazuyuki Sato, Kentaro Kawai, Masaaki Omote, Hitoshi Nishimura
Chemical and Pharmaceutical Bulletin69 ( 6 ) 557 - 563 2021.06
Joint Work
Research paper (scientific journal)
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Ferulic acid alleviates abnormal behaviors in isolation-reared mice via 5-HT1A receptor partial agonist activity
Ryota Araki, Akira Yasubuchi, Marina Ikegaya, Chihiro Hojo, Hayato Tachioka, Kentaro Kawai, Masaaki Omote, Ayami Kita, Takeshi Yabe
Psychopharmacology238 2147 - 2154 2021.04
Joint Work
Research paper (scientific journal)
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Effect of learning dataset for identification of active molecules: a case study of integrin αIIbβ3 inhibitors
Kentaro Kawai, Mami Tomonou, Yume Machida, Yukiko Karuo, Atsushi Tarui, Kazuyuki Sato, Yoshiki Ikeda, Tatsuo Kinashi, Masaaki Omote
Molecular Informatics 202060040 2021.03
Joint Work
Research paper (scientific journal)
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Synthesis of aryl 2-bromo-2-chloro-1,1-difluoroethyl ethers through the base-mediated reaction between phenols and halothane
Yukiko Karuo, Ayaka Kametani, Atsushi Tarui, Kazuyuki Sato, Kentaro Kawai, Masaaki Omote
Beilstein Journal of Organic Chemistry17 89 - 96 2021.01
Joint Work
Research paper (scientific journal)
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Stereoselective synthesis of multisubstituted α-fluoro-β-lactams
Atsushi Tarui, Yukiko Karuo, Kazuyuki Sato, Kentaro Kawai, Masaaki Omote
Current Organic Chemistry24 2169 - 2180 2020.11
Joint Work
Research paper (scientific journal)
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Reductive carbon−carbon bond forming reactions with carbonyls mediated by Rh−H complex
Kazuyuki Sato, Motoyuki Isoda, Atsushi Tarui, Masaaki Omote
European Journal of Organic Chemistry42 6503 - 6511 2020.08
Joint Work
Research paper (scientific journal)
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Synthesis of new fluorescent molecules having an aggregation-induced emission property derived from 4-fluoroisoxazoles
Kazuyuki Sato, Akira Kawasaki, Yukiko Karuo, Atsushi Tarui, Kentaro Kawai, Masaaki Omote
Beilstein Journal of Organic Chemistry16 1411 - 1417 2020.06
Joint Work
Research paper (scientific journal)
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Copper-Catalyzed Oxidative Trifluoromethylation of Terminal Alkenes Using AgCF3
Y. Karuo, T. Hayashi, A. Tarui, K. Sato, K. Kawai, M. Omote
Journal of Organic Chemistry85 ( 7 ) 5104 - 5108 2020.03
Joint Work
Research paper (scientific journal)
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Effect of Structural Descriptors on the Design of Cyclin Dependent Kinase Inhibitors Using Similarity-based Molecular Evolution
K. Kawai, Y. Karuo, A. Tarui, K. Sato, M. Omote
Molecular Informatics39 ( 5 ) 1900126 2020.01
Joint Work
Research paper (scientific journal)
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One-Pot Ring-Opening Peptide Synthesis Using α,α-Difluoro-β-Lactams
Atsushi Tarui, Masakazu Ueo, Marino Morikawa, Masahiko Tsuta, Sumika Iwasaki, Noriko Morishita, Yukiko Karuo, Kazuyuki Sato, Kentaro Kawai, Masaaki Omote
Synthesis52 ( 23 ) 3657 - 3666 2020
Joint Work
Research paper (scientific journal)
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Synthesis of Small Fluorescent Molecules and Evaluation of Photophysical Properties
F. Ogawa, Y. Karuo, R. Yamazawa, K. Miyanaga, K. Hori, K. Tani, K. Yamada, Y. Saito, K. Funabiki, A. Tarui, K. Sato, K. Ito, K. Kawai, M. Omote
Journal of Organic Chemistry85 ( 2 ) 1253 - 1258 2019.12
Joint Work
Research paper (scientific journal)
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Construction of Quaternary Carbon Center by the Reaction of Aza-o-Quinone Methide Mediated Carbocation Intermediate
K. Yukiko, D. Dousei, M. Sakamoto, A. Tarui, K. Sato, K. Kawai, M. Omote
Heterocycles101 ( 1 ) 363 - 372 2019.09
Joint Work
Research paper (scientific journal)
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Structural modification of indomethacin toward selective inhibition of COX-2 with a significant increase in van der Waals contributions
Ikeda A., Funakoshi E., Araki M., Ma B., Karuo Y., Tarui A., Sato K., Okuno Y., Kawai K., Omote M
Bioorganic & Medicinal Chemistry27 1789 - 1794 2019.03
Joint Work
Research paper (scientific journal)
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Lewis acid promoted fluorine-alkoxy group exchange reactions for the synthesis of 5-alkoxy-4,4-difluoroisoxazoline systems
Sato K., Sandford G., Konishi Y., Yanada N., Toda C., Tarui A., Omote M.
Organic & Biomolecular Chemistry 17 2818 - 2823 2019.02
Joint Work
Research paper (scientific journal)
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Proteinase K is an activator for the male‐dependent spermiogenesis pathway in Caenorhabditis elegans: Its application to pharmacological dissection of spermiogenesis
Tatsuya Tajima, Futa Ogawa, Shogo Nakamura, Masaharu Hashimoto, Masaaki Omote, Hitoshi Nishimura
Genes to Cells24 244 - 258 2019.01
Joint Work
Research paper (scientific journal)
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Crystal Structure of (E)-2-(3,3,3-trifluoroprop-1-en-1-yl)aniline
Koji Kubono, Keita Tani, Masaaki Omote, Futa Ogawa and Taisuke Matsumoto
Acta Crystallogr E Crystallogr Commun74 1448 - 1450 2018.09
Joint Work
Research paper (scientific journal)
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Decarboxylative aldol reaction of α,α-difluoro-β-ketocarboxylate salt: a facile method for generation of difluoroenolate
Tarui A., Oduti M., Shinya S., Sato K., Omote M.
RSC Advances8 20568 - 20575 2018.05
Joint Work
Research paper (scientific journal)
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Development of a fluorogenic small substrate for dipeptidyl peptidase-4
Futa Ogawa, Masanori Takeda, Kanae Miyanaga, Keita Tani, Ryuji Yamazawa, Kiyoshi Ito, Atsushi Tarui, Kazuyuki Sato and Masaaki Omote
Beilstein J. Org. Chem.13 2690 - 2697 2017.12
Joint Work
Research paper (scientific journal)
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Rh-Catalyzed reductive Mannich-type reaction and its application towards the synthesis of (±)-ezetimibe
Motoyuki Isoda, Kazuyuki Sato, Atsushi Tarui, Masaaki Omote 他
Beilstein Journal of Organic Chemistry12 1608 - 1615 2016.07
Joint Work
Research paper (scientific journal)
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Synthesis of fluorinated isoxazoles using Selectfluor: preparation and characterization of 4-fluoroisoxazole, 4,4,5-trifluoroisoxazoline and 4,4-difluoro-5-hydroxyisoxazoline systems from one-pot and multi-step processes
Kazuyuki Sato, Graham Sandford, Keiji Shimizu, Satomi Akiyama, Marcus J. Lancashire, Dmitry S. Yufit, Atsushi Tarui, Itsumaro Kumadaki, Shinya Harusawa, Masaaki Omote, Akira Ando
Tetrahedron72 ( 13 ) 1690 - 1698 2016.03
Joint Work
Research paper (scientific journal)
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Nickel-catalyzed Negishi cross-coupling of bromodifluoroacetamides.
Atsushi Tarui, Saori Shinohara, Kazuyuki Sato, Masaaki Omote, Akira Ando
Organic Letters18 ( 5 ) 1128 - 1131 2016.02
Joint Work
Research paper (scientific journal)
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A dramatic enhancing effect of InBr3 towards the oxidative Sonogashira cross-coupling reaction of 2-ethynylanilines.
Akari Ikeda, Masaaki Omote, Kana Kusumoto, Miyuki Komori, Atsushi Tarui, Kazuyuki Sato, Akira Ando
Organic & Biomolecular Chemistry14 ( 6 ) 2127 - 2133 2016.01
Joint Work
Research paper (scientific journal)
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Synthesis of fluorinated Ezetimibe analogue using radical allylation of α-bromo-α-fluoro-β-lactam.
Atsushi Tarui, Ayumi Tanaka, Masakazu Ueo, Kazuyuki Sato, Masaaki Omote, Akira Ando
New Journal of Chemistry39 ( 12 ) 9325 - 9329 2015.09
Joint Work
Research paper (scientific journal)
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One-pot synthesis of 1,3-enynes with a CF3 group on the terminal sp2 carbon by an oxidative Sonogashira cross-coupling reaction.
Akari Ikeda, Masaaki Omote, Kana Kusumoto, Atsushi Tarui, Kazuyuki Sato, Akira Ando
Organic & Biomolecular Chemistry13 ( 33 ) 8886 - 8892 2015.07
Joint Work
Research paper (scientific journal)
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Diastereoselective synthesis of syn-β-lactams using Rh-catalyzed reductive Mannich-type reaction of α,β-unsaturated esters.
Motoyuki Isoda, Kazuyuki Sato, Masato Funakoshi, Keiko Omura, Atsushi Tarui, Masaaki Omote, Akira Ando
Journal of Organic Chemistry80 ( 16 ) 8398 - 8405 2015.07
Joint Work
Research paper (scientific journal)
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Stereoselective Suzuki coupling reaction of an α-bromo-α-fluoro-β-lactam
Atsushi Tarui, Erina Miyata, Kazuyuki Sato, Masaaki Omote, Akira Ando
Synlett1 ( 26 ) 55 - 58 2015.01
Joint Work
Research paper (scientific journal)
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Asymmetric reductive aldol-type reaction with carbonyl compounds using dialkyl tartrate as a chiral ligand
Motoyuki Isoda, Kazuyuki Sato, Yoriko Tokura, Atsushi Tarui, Masaaki Omote, Akira Ando
Chem. Pharm. Bull.10 ( 62 ) 956 - 961 2014.07
Joint Work
Research paper (scientific journal)
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Enantioselective synthesis of α,α-difluoro-β-lactams using amino alcohol ligands
Atsushi Tarui, Takeshi Ikebata, Kazuyuki Sato, Masaaki Omote, Akira Ando
Organic & Biomolecular Chemistry ( 12 ) 6484 - 6489 2014.06
Joint Work
Research paper (scientific journal)
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Csp3-Csp3 homocoupling reaction of benzyl halides catalyzed by rhodium
Kazuyuki Sato, Yuich Inoue, Tomohisa Mori, Atsushi Sakaue, Atsushi Tarui, Masaaki Omote, Itsumaro Kumadaki, Akira Ando
Organic Letters14 ( 16 ) 3756 - 3759 2014.06
Joint Work
Research paper (scientific journal)
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生理活性物質を指向した含フッ素複素環類の合成－フルオロ酢酸エチルおよび含フッ素ビニルシランの利用
Atsushi Tarui,Kazuyuki Sato,Akira Ando
有機合成化学協会誌6 ( 72 ) 680 - 691 2014.06
Joint Work
Research paper (scientific journal)
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Ligand-promoted asymmetric imino-Reformatsky reaction of ethyl dibromofluoroacetate
Atsushi Tarui, Haruka Nishimura, Takeshi Ikebata, Asuka Tahira, Kazuyuki Sato, Hideki Minami, Yoshihisa Miwa, Masaaki Omote, Akira Ando
Organic Letters8 ( 16 ) 2080 - 2083 2014.04
Joint Work
Research paper (scientific journal)
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Oxidative 3,3,3-trifluoropropylation of arylaldehydes.
Akari Ikeda, Masaaki Omote, Shiho Nomura, Miyuu Tanaka, Atsushi Tarui, Kazuyuki Sato, Akira Ando
Beilstein J. Org. Chem9 2417 - 2421 2013.11
Joint Work
Research paper (scientific journal)
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Reductive aldol-type reaction of α,β-unsaturated esters with aldehydes or ketones in the presence of Rh catalyst and Et2Zn.
Kazuyuki Sato, Motoyuki Isoda, Yoriko Tokura, Keiko Omura, Atsushi Tarui, Masaaki Omote, Itsumaro Kumadaki, Akira Ando
Tetrahedron Letters54 ( 44 ) 5913 - 5915 2013.08
Joint Work
Research paper (scientific journal)
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Direct and Diastereoselective Alkylation and Aldol Reactions of α-Bromo-α-fluoro-β-lactams
Atsushi Tarui, Naoto Kawashima, Tetsuya Kawakita, Kazuyuki Sato, Masaaki Omote, Akira Ando
Journal of Organic Chemistry78 ( 16 ) 7903 - 7911 2013.07
Joint Work
Research paper (scientific journal)
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Synthesis of 2-aryl-3-trifluoromethylquinolines using (E)-trimethyl-(3,3,3-trifluoroprop-1-enyl)silane.
Masaaki Omote, Miyuu Tanaka, Miki Tanaka, Akari Ikeda, Atsushi Tarui, Kazuyuki Sato, Akira Ando
Journal of Organic Chemistry78 ( 12 ) 6196 - 6201 2013.05
Joint Work
Research paper (scientific journal)
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New approach to synthesize β,β-difluorohomoallylic alcohols
Masaaki Omote, Tatsuya Miake, Atsushi Tarui, Kazuyuki Sato, Itsumaro Kumadaki, Akira Ando
Journal of Fluorine Chemistry147 1 - 4 2013.03
Joint Work
Research paper (scientific journal)
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Ni-catalyzed α-arylation of α-bromo-α-fluoro-β-lactam: Cross-coupling of a secondary fluorine-containing electrophile
Atsushi Tarui, Shoji Kondo, Kazuyuki Sato, Hideki Minami, Yoshihisa Miwa, Masaaki Omote, Akira Ando
Tetrahedron69 ( 5 ) 1559 - 1565 2013.02
Joint Work
Research paper (scientific journal)
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New approach to 3,3-difluoroallyl alcohol
Tatsuya Miake,Masaaki Omote, Atsushi Tarui, Kazuyuki Sato, John T. Welch, Itsumaro Kumadaki, Akira Ando
Journal of Fluorine Chemistry144 114 - 117 2012.08
Joint Work
Research paper (scientific journal)
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Simple Synthesis of β-Trifluoromethylstyrenes Using (E)-Trimethyl-(3,3,3-trifluoroprop-1-enyl)silane
Masaaki Omote, Miyuu Tanaka, Akari Ikeda, Shiho Nomura, Atsushi Tarui, Kazuyuki Sato, Akira Ando
Organic Letters14 ( 9 ) 2286 - 2289 2012.04
Joint Work
Research paper (scientific journal)
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Reductive Reformatsky-Honda Reaction of α,β-Unsuturated Esters: Facile Formation of 1,3-Dicarbonyl Compounds and β-Hydroxy Esters.
K. Sato, A. Tarui, M. Omote, I. Kumadaki, A. Ando
Advanced Synthesis & Catalysis354 ( 2月3日 ) 510 - 514 2012.02
Joint Work
Research paper (scientific journal)
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Trifluoromethylation at the α-position of α,β-unsaturated ketones: 4-Phenyl-3-trifluoromethyl-2-butanone.
Kazuyuki Sato, Masaaki Omote, Atsushi Tarui, Itsumaro Kumadaki, Akira Ando
Organic tyntheses89 374 - 379 2012.02
Joint Work
Research paper (scientific journal)
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Stereoselective Synthesis of α-Fluorinated Amino Acid Derivatives
Atsushi Tarui, Kazuyuki Sato, Masaaki Omote, Itsumaro Kumadaki, Akira Ando
Advanced Synthesis & Catalysis352 ( 16 ) 2733 - 2744 2010.11
Joint Work
Research paper (scientific journal)
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Diastereoselective Synthesis of 2-Fluoroaziridine-2-carboxylates by Reformatsky-type Aza-Darzens Reaction
Atsushi Tarui, Naoto Kawashima, Kazuyuki Sato, Masaaki Omote, Akira Ando
Tetrahedron Letters51 ( 32 ) 4246 - 4249 2010.08
Joint Work
Research paper (scientific journal)
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Trifluoromethylation of Organic Compounds and Related Reactions
Kazuyuki Sato, Atsushi Tarui, Masaaki Omote, Akira Ando, Itsumaro Kumadaki
Synthesis11 1865 - 1882 2010.06
Joint Work
Research paper (scientific journal)
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Simple, chemoselective, and diastereoselective Reformatsky-type synthesis of α-bromo-α-fluoro-β-lactams
Atsushi Tarui, Naoto Kawashima, Kazuyuki Sato, Masaaki Omote, Yoshihisa Miwa, Hideki Minami, Akira Ando
Tetrahedron Letters51 ( 15 ) 2000 - 2003 2010.04
Joint Work
Research paper (scientific journal)
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Mechanistic Studies on α-Trifluoromethylation of Ketones via Silyl Enol Ethers and Its Application to Other Carbonyl Compounds.
Kazuyuki Sato, Takashi Yuki, Ryoji Yamaguchi, Tetsuya Hamano, Atsushi Tarui, Masaaki Omote, Itsumaro Kumadaki, Akira Ando
J. Org. Chem.74 ( 10 ) 3815 - 3819 2009.04
Joint Work
Research paper (scientific journal)
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Enantioselective Alkynylation of Aldehydes with Chiral β-Imino α-Perfluoroalkylpropanol Derivatives.
Masaaki Omote, YusukeEto, Atsushi Tarui, Kazuyuki Sato, Akira Ando
Tetrahedron:Asymmetry20 ( 5 ) 602 - 604 2009.03
Joint Work
Research paper (scientific journal)
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Direct synthesis of 1,3-diketones by Rh-catalyzed reductive α-acylation of enones.
K. Sato, S. Yamazoe, R. Yamamoto, S. Ohata, A. Tarui, M. Omote, I. Kumadaki, A. Ando
Organic Letters10 ( 12 ) 2405 - 2408 2008.05
Joint Work
Research paper (scientific journal)
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Zn-mediated rhodium-catalyzed α-trifluoromethylation of ketones via silyl enol ethers.
K. Sato, T. Yuki, A. Tarui, M. Omote, I. Kumadaki, A. Ando
Tetrahedron Letters49 ( 22 ) 3558 - 3561 2008.04
Joint Work
Research paper (scientific journal)
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Rhodium-catalyzed Reformatsky-type reaction for asymmetric synthesis of difluoro-β-lactams using menthyl group as a chiral auxiliary.
A. Tarui, D. Ozaki, N. Nakajima, Y. Yokota, Y. S. Sokeirik, K. Sato, M. Omote, I. Kumadaki, A. Ando
Tetrahedron Letters49 ( 24 ) 3839 - 3843 2008.04
Joint Work
Research paper (scientific journal)
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Synthesis of recyclable fluorous chiral ligands and evaluation of their catalytic activity toward asymmetric addition of dimethylzinc to aldehydes.
Y. S. Sokeirik, A. Hoshina, M. Omote, K. Sato, A. Tarui, I. Kumadaki, A. Ando
Chem. Asian J.3 ( 10 ) 1850 - 1856 2008
Joint Work
Research paper (scientific journal)
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Rh-catalyzed novel α-fluoroalkylation of α,β-unsaturated ketones and its mechanism.
K. Sato, Y. Ishida, E. Murata, Y. Oida, Y. Mori, M. Okawa, K. Iwase, A. Tarui, M. Omote, I. Kumadaki, A. Ando
Tetrahedron63 ( 51 ) 12735 - 12739 2007.10
Joint Work
Research paper (scientific journal)
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Rhodium-catalyzed α-fluoroalkylation reaction of ketones using silyl enol ethers.
K. Sato, M. Higashinagata, T. Yuki, A. Tarui, M. Omote, I. Kumadaki, A. Ando
Journal of Fluorine Chemistry129 ( 1 ) 51 - 55 2007.09
Joint Work
Research paper (scientific journal)
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The diastereoselective synthesis of difluoro-β-lactam using Reformatsky-Honda reaction.
A. Tarui, K. Kondo, H. Taira, K. Sato, M. Omote, I. Kumadaki, A. Ando
Heterocycles73 ( 1 ) 203 - 208 2007.08
Joint Work
Research paper (scientific journal)
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Formation of quaternary carbon center with a trifluoromethyl group using a Pd-catalyzed allylation reaction.
K. Sato, Y. Takiguchi, Y. Yoshizawa, K. Iwase, Y. Shimizu, A. Tarui, M. Omote, I. Kumadaki, A. Ando
Chem. Pharm. Bull.55 ( 11 ) 1593 - 1596 2007.08
Joint Work
Research paper (scientific journal)
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Synthesis of a fluorous ligand and its application for asymmetric addition of dimethylzinc to aldehydes.
Y. S. Sokeirik, H. Mori, M. Omote, K. Sato, A. Tarui, I. Kumadaki, A. Ando
Organic Letters9 ( 10 ) 1927 - 1929 2007.02
Joint Work
Research paper (scientific journal)
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Syntheses of Chiral β-Amino α-Perfluoroalkylpropanol Derivatives
M. Omote, Y. Eto, A. Tarui, K. Sato, A. Ando
Tetrahedron:Asymmetry18 ( 23 ) 2768 - 2772 2007
Joint Work
Research paper (scientific journal)
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Synthesis of axially dissymmetric ligands with two chiral centers of perfluoroalkyl carbinol moiety, and their application to asymmetric syntheses.
M. Omote, K. Sato, A. Ando, I. Kumadaki
Curr. Org. Synth.4 ( 2 ) 137 - 150 2007
Joint Work
Research paper (scientific journal)
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Enantioselective Addition of Methyl Group to Aldehydes Catalyzed by Titanium Complex of Fluorous Ligand
M. Omote, N. Tanaka, A. Tarui, K. Sato, I. Kumadaki, A. Ando
Tetrahedron Letters48 ( 17 ) 2989 - 2991 2007
Joint Work
Research paper (scientific journal)
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High Asymmetric Induction Using a Diastereometric Mixture of Axially Dissymmetric Ligands
M. Omote, Y. Nishimura, K. Sato, A. Ando, I. Kumadaki
J. Fluorine Chem.127 ( 7 ) 977 - 979 2006
Joint Work
Research paper (scientific journal)
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Application of Axially Dissymmetric Ligand Recoverable with Fluorous Solvent as a Chiral Auxiliary
M. Omote, Y. Nishimura, K. Sato, A. Ando, I. Kumadaki
J. Fluorine Chem.127 ( 1 ) 74 - 78 2006
Joint Work
Research paper (scientific journal)
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Novel Reduction of Perfluoroalkyl Ketones with Lithium Alkoxides
Y. S. Sokeirik, K. Sato, M. Omote, A. Ando, I. Kumadaki
J. Fluorine Chem.127 ( 1 ) 150 - 152 2006
Joint Work
Research paper (scientific journal)
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New Axially Dissymmetric Ligand Recoverable with Fluorous Solvent
M. Omote, Y. Nishimura, K. Sato, A. Ando, I. Kumadaki
Tetrahedron62 ( 8 ) 1886 - 1894 2006
Joint Work
Research paper (scientific journal)
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Asymmetric Reduction of Perfluoroalkyl Ketones with Chiral Lithium Alkoxides
Y. S. Sokeirik, K. Sato, M. Omote, A. Ando, I. Kumadaki
Tetrahedron Lett.47 ( 16 ) 2821 - 2824 2006
Joint Work
Research paper (scientific journal)
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Trifluoromethylation at the α-position of α,β-unsaturated ketones: 4-Phenyl-3-(trifluoromethyl)butan-2-one.
K. Sato, M. Omote, A. Ando, I. Kumadaki
Organic Syntheses83 177 - 183 2006
Joint Work
Research paper (scientific journal)
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Synthesis of a Schiff's Base Chiral Ligand with a Trifluoromethyl Carbinol Moiety
Y. S. Sokeirik, M. Omote, K. Sato, I. Kumadaki, A. Ando
Tetrahedron:Asymmetry17 ( 18 ) 2654 - 2658 2006
Joint Work
Research paper (scientific journal)
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The simple and selective synthesis of 3-amino-2,2-difluorocarboxylic esters and difluoro-β-lactams using ethyl bromodifluoroacetate in the presence of rhodium catalyst.
K. Sato, A. Tarui, S. Matsuda, M. Omote, A. Ando, I. Kumadaki
Tetrahedron Letters46 ( 45 ) 7679 - 7681 2005.09
Joint Work
Research paper (scientific journal)
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Synthesis of 2-chloro-1,1-difluoroallyl mesylates through novel rearrangement and C-C bond formation by their Pd-catalyzed reaction with diethylzinc.
A. Ando, M. Nishihara, K. Sato, M. Omote, I. Kumadaki
Journal of Fluorine Chemistry126 ( 5 ) 765 - 770 2005.02
Joint Work
Research paper (scientific journal)
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The Catalytic Mannich Reaction of 1,1-Difluoro-2-trialkyl(aryl)silyl-2-trimethylsilyloxyethenes: Preparation of β-Amino Acid Derivatives
W. J. Chung, M, Omote, John T. Welch
J. Org. Chem.70 ( 19 ) 7784 - 7787 2005
Joint Work
Research paper (scientific journal)
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Synthesis of new axially dissymmetric ligand with large perfluoroalkyl groups
M. Omote, Y. Nishimura, K. Sato, A. Ando, I. Kumadaki
Tetrahedron Lett.46 ( 2 ) 319 - 322 2005
Joint Work
Research paper (scientific journal)
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Recycling of fluorinated axially dissymmetric ligand with fluorous solvent
M. Omote, Y. Nishimura, K. Sato, A. Ando, I. Kumadaki
J. Fluorine Chem.126 ( 3 ) 407 - 409 2005
Joint Work
Research paper (scientific journal)
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Rhodium-catalyzed novel trifluoromethylation at the α-position of α,β-unsaturated ketones.
K. Sato, M. Omote, A. Ando, I. Kumadaki
Organic Letters6 ( 23 ) 4359 - 4361 2004.08
Joint Work
Research paper (scientific journal)
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Reaction of ethyl bromodifluoroacetate in the presence of copper powder.
K. Sato, M. Omote, A. Ando, I. Kumadaki
Journal of Fluorine Chemistry125 ( 4 ) 509 - 515 2004
Joint Work
Research paper (scientific journal)
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Rhodium-catalyzed Reformatsky-type reaction of ethyl bromodifluoroacetate.
K. Sato, A. Tarui, T. Kita, Y. Ishida, H. Tamura, M. Omote, A. Ando, I. Kumadaki
Tetrahedron Letters45 ( 29 ) 5735 - 5737 2004
Joint Work
Research paper (scientific journal)
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New approach to a novel axially chiral ligand showing spontaneous enrichment of axial chirality.
T. Hasegawa, M. Omote, K. Sato, A. Ando, I. Kumadaki
Chem. Pharm. Bull.51 ( 3 ) 265 - 267 2003
Joint Work
Research paper (scientific journal)
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Hetero Diels-Alder reaction catalyzed by new axially dissymmetric ligands with fluorinated chiral centers.
M. Omote, T. Hasegawa, K. Sato, A. Ando, I. Kumadaki
Heterocycles59 ( 2 ) 501 - 504 2003
Joint Work
Research paper (scientific journal)
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1,4-Addition reaction of ethyl bromodifluoroacetate to Michael acceptors in the presence of copper powder. -Improvement of the reaction using TMEDA as an additive-
K. Sato, S. Nakazato, H. Enko, H. Tsujita, K. Fujita, T. Yamamoto, M. Omote, A. Ando, I. Kumadaki
Journal of Fluorine Chemistry121 ( 1 ) 105 - 107 2003
Joint Work
Research paper (scientific journal)
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Reaction of Halothane with sec-butyllithium in the presence of zinc halides - One-pot preparation of chlorodifluorovinylzinc reagent and its derivatization to α-chloro-β,β-difluorostyrene.
M. Nishihara, Y. Nakamura, N. Maruyama, K. Sato, M. Omote, A. Ando, I. Kumadaki
Journal of Fluorine Chemistry122 ( 2 ) 247 - 249 2003
Joint Work
Research paper (scientific journal)
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Reaction of Halothane with carbonyl compounds in the presence of base.
A. Ando, J. Takahashi, Y. Nakamura, N. Maruyama, M. Nishihara, K. Fukushima, J. Moronaga, M. Inoue, K. Sato, M. Omote, I. Kumadaki
Journal of Fluorine Chemistry123 ( 2 ) 283 - 285 2003
Joint Work
Research paper (scientific journal)
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Synthesis of 4,4-difluoro-α-tocopherol using a cross-coupling reaction of bromodifluoroacetate with aryl iodide in the presence of copper powder.
K. Sato, T. Nishimoto, K. Tamoto, M. Omote, A. Ando, I. Kumadaki
Heterocycles56 ( 1-2 ) 403 - 412 2002
Joint Work
Research paper (scientific journal)
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Syntheses of Chiral Fluorine Analogs of Hematoporphyrin
M. Omote, A. Ando, K. Sato, I. Kumadaki
Tetrahedron57 ( 38 ) 8085 - 8094 2001
Joint Work
Research paper (scientific journal)
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Synthesis of fluorinated analogs of natural porphyrins potentially useful for the diagnosis and therapy of cancer
I. Kumadaki, A. Ando, M. Omote
Journal of Fluorine Chemistry109 ( 1 ) 67 - 81 2001
Joint Work
Research paper (scientific journal)
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Synthesis of α-(trifluoromethyl)pyrrolidines by cyclization of N-tosyl-α-(trifluoromethyl)homoallylamine derivatives.
I. Kumadaki, S. Jonoshita, K. Sato, M. Omote, A. Ando
Heterocycles54 ( 2 ) 589 - 592 2001
Joint Work
Research paper (scientific journal)
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Synthesis of new fluorovinylzinc reagents and their application for synthesis of fluorine analogs of protoporphyrin.
T. Shigeoka, Y. Kuwahara, K. Watanabe, K. Sato, M. Omote, A. Ando, I. Kumadaki
Journal of Fluorine Chemistry103 ( 1 ) 99 - 103 2000
Joint Work
Research paper (scientific journal)
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Synthesis of fluorine anaolgs of protoporphyrin potentially useful for diagnosis and therapy of cancer. III. Synthesis of (2,2-difluorovinyl)trifluorovinyl- and (1-chloro-2,2-difluorovinyl)(2,2-difluorovinyl)deuteroporphyrins.
T. Shigeoka, Y. Kuwahara, K. Watanabe, K. Sato, M. Omote, A. Ando, I. Kumadaki
Heterocycles51 ( 1 ) 383 - 388 2000
Joint Work
Research paper (scientific journal)
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Synthesis of new synthons for organofluorine compounds from Halothane containing sulfur functional groups.
M. Kato, K. Maeda, K. Sato, M. Omote, A. Ando, I. Kumadaki
Chem. Pharm. Bull.48 ( 5 ) 683 - 686 2000
Joint Work
Research paper (scientific journal)
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Michael-type reaction of ethyl bromodifluoroacetate with α,β-unsaturated carbonyl compounds in the presence of copper powder.
K. Sato, M. Tamura, K. Tamoto, M. Omote, A. Ando, I. Kumadaki
Chem. Pharm. Bull.48 ( 7 ) 1023 - 1025 2000
Joint Work
Research paper (scientific journal)
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Synthesis of organofluorine compounds using the ene type reaction of N-(p-toluenesulfonyl)-trifluoroacetaldehyde imine.
I. Kumadaki, S. Jonoshita, A. Harada, M. Omote, A. Ando
Journal of Fluorine Chemistry97 ( 1-2 ) 61 - 63 1999
Joint Work
Research paper (scientific journal)
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Synthesis of organofluorine compounds using the ene reaction of N-(p-toluenesulfonyl)-trifluoroacetaldehyde imine.
S. Jonoshita, A. Harada, M. Omote, A. Ando, I. Kumadaki
Chem. Pharm. Bull.47 ( 5 ) 656 - 662 1999
Joint Work
Research paper (scientific journal)
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An efficient route to formyldeuteroporphyrins and their Wittig reaction.
A. Ando, M. Yamazaki, M. Komura, Y. Sano, N. Hattori, M. Omote, I. Kumadaki
Heterocycles50 ( 2 ) 913 - 918 1999
Joint Work
Research paper (scientific journal)
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Synthesis of alkenyl- and aryldifluoroacetate using a copper complex from ethyl bromodifluoroacetate.
K. Sato, R. Kawata, F. Ama, M. Omote, A. Ando, I. Kumadaki
Chem. Pharm. Bull.47 ( 7 ) 1013 - 1016 1999
Joint Work
Research paper (scientific journal)
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Synthesis of fluorine analogs of protoporphyrin potenntially useful for diagnosis and therapy of cancer. IV. Synthesis of (trifluorovinyl)vinyl- and (1-chloro-2,2-difluorovinyl)vinyldeutero-porphyrins.
T. Shigeoka, Y. Kuwahara, K. Watanabe, K. Sato, M. Omote, A. Ando, I. Kumadaki
Chem. Pharm. Bull.47 ( 9 ) 1326 - 1329 1999
Joint Work
Research paper (scientific journal)
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A novel axially dissymmetric ligand with chiral 2,2,2-trifluoro-1-hydroxyethyl groups.
M. Omote, A. Kominato, M. Sugawara, K. Sato, A. Ando, I. Kumadaki
Tetrahedron Letters40 ( 30 ) 5583 - 5585 1999
Joint Work
Research paper (scientific journal)
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Optical resolution and asymmetric synthesis of benzyl 3,5-dimethyl-4-(2,2,2-trifluoro-1-hydroxy-ethyl)pyrrole-2-carboxylate.
M. Omote, T. Matsumoto, A. Ando, T. Takagi, M. Koyama, I. Kumadaki, M. Shiro
Heterocycles47 ( 1 ) 65 - 68 1998
Joint Work
Research paper (scientific journal)
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Reaction of Halothane with carbonyl compounds in the presence of lithium diisopropylamide.
T. Takagi, K. Kanai, M. Omote, A. Ando, I. Kumadaki
Journal of Fluorine Chemistry89 ( 2 ) 233 - 234 1998
Joint Work
Research paper (scientific journal)
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Optical resolution of (2,2,2-trifluoro-1-hydroxyethyl)deuteroporphyrins.
M. Omote, T. Matsumoto, A. Ando, T. Takagi, M. Koyama, I. Kumadaki
Heterocycles46 ( 1 ) 259 - 266 1997
Joint Work
Research paper (scientific journal)
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Synthesis of a fluorine analog of hematoporphyrin by ring closure.
M. Omote, A. Ando, T. Takagi, M. Koyama, I. Kumadaki
Tetrahedron52 ( 44 ) 13961 - 13970 1996
Joint Work
Research paper (scientific journal)
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Synthesis of formyl(2,2,2-trifluoro-1-hydroxyethyl)deuteroporphyrins and their derivatization to porphyrin derivatives with elongated side-chains.
M. Omote, A. Ando, T. Takagi, M. Koyama, I. Kumadaki
Chem. Pharm. Bull.43 ( 7 ) 1107 - 1110 1995
Joint Work
Research paper (scientific journal)
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Synthesis of fluorine analogs of hematoporphyrin. II.
M. Omote, A. Ando, M. Koyama, T. Takagi, I. Kumadaki
Heterocycles39 ( 1 ) 381 - 384 1994
Joint Work
Research paper (scientific journal)
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Synthesis of fluorine analogs of hematoporphyrin.
A. Ando, T. Kitamura, S. Aono, H. Sato, M. Omote, M. Koyama, T. Takagi, T. Miki, I. Kumadaki
Heterocycles35 ( 2 ) 1309 - 1312 1993
Joint Work
Research paper (scientific journal)