UNO Kyosuke (UNO Kyosuke)

写真a

Job title

Lecturer

Graduating School 【 display / non-display

  • Kanazawa University   Faculty of Pharmaceutical Science   Graduated 

Graduate School 【 display / non-display

  • Kanazawa University   Graduate School, Division of National Science and Technology   Master's Course  Completed 

  • Kanazawa University   Graduate School, Division of National Science and Technology   Doctor's Course  Completed 

Degree 【 display / non-display

  • Kanazawa University  -  修士(薬学)

  • Kanazawa University  -  博士(薬学)

Academic Society Affiliations 【 display / non-display

  • 日本薬理学会
  • 日本薬学会
  • 日本神経化学会
  • 日本神経精神薬理学
  • 日本アルコール・アディクション医学会

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Research field 【 display / non-display

  • Life Science / Clinical pharmacy

  • Life Science / Pharmaceutical hygiene and biochemistry

  • Life Science / Psychiatry

  • Life Science / Pharmacology

 

Papers 【 display / non-display

  • Delayed Expression of Both GABABR1 and GABABR2 Subunits in Murine Hippocampal Dentate Gyrus After a Single Systemic Injection of Trimethyltin.

    Onishi Y, Yamamura Y, Hosogi M, Higashi H, Ogita K, Kinjo T, Uno K, Yoneda Y, Kuramoto N.

    Neurochem Res47 ( 9 )   2022.07

    Joint Work

    Research paper (scientific journal)

  • Knockdown of Piccolo in the nucleus accumbens suppresses methamphetamine‐induced hyperlocomotion and conditioned place preference in mice

    Kusui Y, Izuo N, Uno K, Ge B, Muramatsu SI, Nitta A.

    Neurochem Res47 ( 9 )   2022.07

    Joint Work

    Research paper (scientific journal)

  • Shati/Nat8l overexpression improves cognitive decline by upregulating neuronal trophic factor in Alzheimer's disease model mice

    Chino K, Izuo N, Noike H, Uno K, Kuboyama T, Tohda C, Muramatsu SI, Nitta A.

    Neurochem Res47 ( 9 )   2022.06

    Joint Work

    Research paper (scientific journal)

  • Investigating DNA Methylation of SHATI/NAT8L Promoter Sites in Blood of Unmedicated Patients with Major Depressive Disorder

    Miyanishi H, Uno K, Iwata M, Kikuchi Y, Yamamori H, Yasuda Y, Ohi K, Hashimoto R, Hattori K, Yoshida S, Goto YI, Sumiyoshi T, Nitta A.

    Biol Pharm Bull   2020.07

    Joint Work

    Research paper (scientific journal)

  • Glycine receptor α4 subunit facilitates the early embryonic development in mice.

    Nishizono H, Darwish M, Endo TA, Uno K, Abe H, Yasuda R.

    Reproduction.   2020.01

    Joint Work

    Research paper (scientific journal)

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Books 【 display / non-display

  • Shati/Nat8l and N-acetylaspartate (NAA) have important roles in regulating nicotinic acetylcholine receptors in neuronal and psychiatric diseases in animal models and humans

    Atsumi Nitta● Hiroshi Noike● Kazuyuki Sumi● Hajime Miyanishi● Takuya Tanaka● Kazuya Takaoka● Miyuki Nagakura● Noriyuki Iegaki● Jin-ichiro Kaji● Yoshiaki Miyamoto● Shin-Ichi Muramatsu● Kyosuke Uno​Scholarly book  Joint author

    Springer Nature  2019.04

Review Papers 【 display / non-display

  • 前頭野での意思決定暗号の解読

    宇野恭介

    ファルマシア    2020.08

    Article, review, commentary, editorial, etc. (scientific journal)  Single Work

  • Apelin/Apelin Receptor System: Molecular Characteristics, Physiological Roles, and Prospects as a Target for Disease Prevention and Pharmacotherapy

    Kinjo T, Higashi H, Uno K, Kuramoto N.

    Curr Mol Pharmacol.    2020.06

    Article, review, commentary, editorial, etc. (scientific journal)  Joint Work

  • 薬物依存において発現変化する分子とそのシグナル経路.

    宮本嘉明, 傅柯荃, 宇野恭介, 新田淳美.

    分子医学.    2018.01

    Article, review, commentary, editorial, etc. (scientific journal)  Joint Work

  • 依存症の分子病態解析.

    新田淳美, 宇野恭介, 鍋島俊隆, 宮本嘉明.

    脳21    2016.01

    Article, review, commentary, editorial, etc. (scientific journal)  Joint Work

  • 薬物依存関連新規分子の生理機能解明について.

    宮本嘉明, 斎鹿絵里子, 堀悦郎, 家垣典幸, 石川雄大, 鷲見和之, 鍋島俊隆, 村松慎一, 西条寿夫, 宇野恭介, 新田淳美.

    日本神経精神薬理学雑誌    2013.08

    Article, review, commentary, editorial, etc. (scientific journal)  Joint Work

Presentations 【 display / non-display

  • KCC2阻害剤VU0463271による神経細胞の興奮に伴うミトコンドリア脱分極の抑制作用

    日本薬学会第143年会  札幌(北海道大学)  Domestic presentation  Poster presentation 

    2023.03
     
     

  • マウス線条体でのPenk過剰発現はうつ抵抗性を示す

    日本薬学会第143年会  札幌(北海道大学)  Domestic presentation  Poster presentation 

    2023.03
     
     

  • CRISPR/Cas9システムを用いたうつ関連性遺伝子の探索

    日本薬学会第143年会  札幌(北海道大学)  Domestic presentation  Poster presentation 

    2023.03
     
     

  • Behavioral analysis induced by P5 combined expression-induced GABABR2 dephosphorylation in mouse hippocampus

    日本薬学会第143年会  札幌(北海道大学)  Domestic presentation  Poster presentation 

    2023.03
     
     

  • Behavioral analysis of mice overexpressing PP5 specifically in the mice CA3 region of hippocampus.

    Japan Basic and Clinical Pharmacology Week 2022  横浜  Domestic presentation  Poster presentation 

    2022.11
    -
    2022.12

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Industrial Property 【 display / non-display

  • プロポリスのミセル化抽出物を有効成分とする認知機能改善剤

    Patent

    Application Number:特願2016-151747 

    新田淳美, 鷲見和之, 野池悠, 宇野恭介

    Application Date:2016.08.02 

    Country of applicant: Domestic 

  • 精神障害の検査方法および検査キット

    Patent

    Application Number:PCT-TU21-85 51400342321 

    新田淳美 宇野恭介

    Application Date:2014.02.18 

    Country of applicant: Domestic 

  • 精神障害の検査方法および検査キット

    Patent

    Application Number:特願2013-29643 

    新田淳美 宇野恭介

    Application Date:2013.02.19 

    Country of applicant: Domestic 

Research Grants and Projects 【 display / non-display

  • 線条体でのオピオイドペプチドによるうつ脆弱性と痛覚反応性の関連に関する研究

    2022.04 - 2025.03

    科研費 

  • 筋萎縮性側索硬化症の病態進行の鍵遺伝子の解明ー遺伝子治療を目指してー

    2021.04 - 2024.03

    科研費 

  • 経口投与可能な神経細胞特異的カリウム排出促進薬による神経変性予防効果の実証

    2021.04 - 2024.03

    科研費 

  • 線条体におけるうつ病脆弱形成遺伝子の新規探索

    2019.04 - Now

    科研費 

  • 薬物乱用防止を目指した薬物乱用患者とSHATI/NAT8Lの遺伝子関連解析

    2017.04 - 2019.03

    科研費 

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