KONISHI Motomi (KONISHI Motomi)

写真a

Job title

Professor

Homepage URL

http://www.setsunan.ac.jp/

Research Interests 【 display / non-display

  • 天然物化学

  • 分析科学

  • 物理系薬学

Graduating School 【 display / non-display

  • Kobe Pharmaceutical University   Faculty of Pharmaceutical Science   衛生薬学科  Graduated 

Graduate School 【 display / non-display

  • Kobe Pharmaceutical University   Graduate School, Division of Pharmaceutical Sciences   Master's Course  Completed 

Degree 【 display / non-display

  • Kobe Pharmaceutical University  -  薬学士

  • Kobe Pharmaceutical University  -  修士

  • Kanazawa University  -  博士(薬学)

Academic Society Affiliations 【 display / non-display

  • 日本薬学会
  • 日本分析化学会
  • 日本生化学会
  • 日本生薬学会

Research field 【 display / non-display

  • Life Science / Pharmaceutical analytical chemistry and physicochemistry

 

Research Career 【 display / non-display

  • アミロイドβを加水分解するペプチドの立体構造解析

    Project Year:2014.04  -  Now 

    Keyword:加水分解酵素、アミロイドβ、ペプチド

  • Search for Matrix Metalloproteinase Inhibitors

    Classification of research:Collaboration in Organization 

    Project Year:

    Keyword:MMP, Inhibitor

  • 動植物中の抗転移物質の構造解析

    Project Year:

  • Studies on Cardiac Steroids

    Project Year:

    Keyword:Bufadienolide,Na+,K+-ATPase

  • 抗転移物質の検索

    Project Year:

Papers 【 display / non-display

  • Five-mer peptides prevent short-term spatial memory defcits in Aβ25-35-induced Alzheimer’s model mouse by suppressing Aβ25-35 aggregation and resolving its aggregate form

    Rina Nakamura, Motomi Konishi , Youichirou Higashi , Motoaki Saito, Toshifumi Akizawa

    Alzheimer’s Research & Therapy 15   83   2023.04

    Joint Work

    Research paper (scientific journal)

    DOI

  • Structure–Activity Relationship of 5-mer Catalytides, GSGYR and RYGSG

    Rina Nakamura; Toshifumi Akizawa; Motomi Konishi

    Biomolecules12 ( 12 )   2022.11

    Joint Work

    Research paper (scientific journal)

    DOI

  • Direct Delivery of ANA-TA9, a Peptide Capable of Aβ Hydrolysis, to the Brain by Intranasal Administration

    Yusuke Hatakawa, Akiko Tanaka, Tomoyuki Furubayashi, Rina Nakamura, Motomi Konishi, Toshifumi Akizawa, Toshiyasu Sanane,,

    Pharmaceutics13 ( 10 )   pharmaceutics13101673   2021.10

    Joint Work

    Research paper (scientific journal)

    DOI

  • Amyloid-beta cleavage by ANA-TA9, a synthetic peptide from the ANA/BTG3 Box A region

    Yusuke Hatakawa, Rina Nakamura, Motomi Konishi, Toshiyasu Sanane, Akiko Tanaka, Akira Matsuda, Motoaki Saito, Toshifumi Akizawa

    Alzheimers Dement (N Y)7 ( 1 )   e12146   2021.03

    Joint Work

    Research paper (scientific journal)

    DOI

  • JAL-TA9 Inhibits Aggregation of hPrP180-192 through the Cleavage Reaction

    R. Nakamura, M. Konishi,Y. Sakaguchi, Y. Hatakawa, T. Akizawa,

    J Pharm Pharmacol Res4 ( 2 ) 23 - 33   2020.06

    Joint Work

    Research paper (scientific journal)

    DOI

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Books 【 display / non-display

  • 「薬学テキストシリーズ」 分析化学Ⅰ 定量分析編 第2版

    中込和哉、秋澤俊史、小西元美、小林茂樹、西宮一総、馬渡健一 (Part : 1章、4章)  Textbook, survey, introduction  Joint author

    朝倉書店  2018.04

  • 薬剤師に必要な臨床機器分析

    秋澤俊史、川原正博、小谷明、谷本剛、袴田秀樹、道田隆 (Part : 第5章 MS)  Scholarly book  Joint author

    廣川書店  2010.08

Presentations 【 display / non-display

  • Structural analysis of the peptide GSGFK that inhibits amyloid β25-35 aggregation

    The 143rd Annual Meeting of the Pharmaceutical Society of Japan  Sapporo (Hokkaido Univ.)  Domestic presentation  Poster presentation 

    2023.03
     
     

    [Proceedings] 日本薬学会第143年会  2023.03

  • Structural analysis of peptides (GSGNR,GSGHR) that inhibit amyloid-β aggregation

    72st Kansai Regional Meeting of the Pharmaceutical Society of Japan  大阪  Domestic presentation  Poster presentation 

    2022.10
     
     

    [Proceedings] 72st Kansai Regional Meeting of the Pharmaceutical Society of Japan  2022.10

  • Docking simulation of 5-Mer Catalytide (GSGFK) and α-Synuclein 61-84

    72st Kansai Regional Meeting of the Pharmaceutical Society of Japan  大阪  Domestic presentation  Poster presentation 

    2022.10
     
     

    [Proceedings] 72st Kansai Regional Meeting of the Pharmaceutical Society of Japan  2022.10

  • Identification of the seeds peptides for the drug of Parkinson's disease

    34rd Symposium on Biomedical-analytical Sciences  Chiba  Domestic presentation  Oral presentation (general) 

    2022.09
     
     

    [Proceedings] 34rd Symposium on Biomedical-analytical Sciences  48  -  48  2022.09

  • Docking simulation of 5-Mer Catalytide (GSGNR) and Aβ25-35

    71st Kansai Regional Meeting of the Pharmaceutical Society of Japan  大阪  Domestic presentation  Poster presentation 

    2021.10
     
     

    [Proceedings] 71st Kansai Regional Meeting of the Pharmaceutical Society of Japan

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Other research activities 【 display / non-display

  • Studies on Cardiac Steroids

    Other 

    1990