論文 - 長谷部　茂

Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes.

Kensuke Matsumura, Kaoru Seiriki, Shota Okada, Masashi Nagase, Shinya Ayabe, Ikuko Yamada, Tamio Furuse, Hirotoshi Shibuya, Yuka Yasuda, Hidenaga Yamamori, Michiko Fujimoto, Kazuki Nagayasu, Kana Yamamoto, Kohei Kitagawa, Hiroki Miura, Nanaka Gotoda-Nishimura, Hisato Igarashi, Misuzu Hayashida, Masayuki Baba, Momoka Kondo, Shigeru Hasebe, 他17名

Nature Communications   2020年02月

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研究論文（学術雑誌）

mS-11, a mimetic of the mSin3-binding helix in NRSF, ameliorates social interaction deficits in a prenatal valproic acid-induced autism mouse model.

Haruki Kawase, Yukio Ago, Megumi Naito , Momoko Higuchi, Yuta Hara, Shigeru Hasebe, 他6名

Pharmacology Biochemistry and Behavior   2018年11月

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研究論文（学術雑誌）

Oxytocin attenuates deficits in social interaction but not recognition memory in a prenatal valproic acid-induced mouse model of autism.

Yuta Hara, Yukio Ago, Momoko Higuchi, Shigeru Hasebe, Takanobu Nakazawa, 他3名

Hormones and Behavior   2017年09月

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研究論文（学術雑誌）

Risperidone and aripiprazole alleviate prenatal valproic acid-induced abnormalities in behaviors and dendritic spine density in mice

Yuta Hara, Yukio Ago, Atsuki Taruta, Shigeru Hasebe, Haruki Kawase, 他6名

Psychopharmacology (Berl)   2017年08月

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研究論文（学術雑誌）

Prenatal exposure to valproic acid increases miR-132 levels in the mouse embryonic brain.

Yuta Hara, Yukio Ago, Erika Takano, Shigeru Hasebe, Takanobu Nakazawa, 他3名

Molecular Autism   2017年06月

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研究論文（学術雑誌）

Environmental enrichment attenuates behavioral abnormalities in valproic acid-exposed autism model mice.

Hiroshi Yamaguchi, Yuta Hara, Yukio Ago, Erika Takano, Shigeru Hasebe, 他4名

Behavioral Brain Research   2017年06月

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研究論文（学術雑誌）

Regulation of emotional behaviors by juvenile environmental factors.

田熊 一敞, 吾郷 由希夫, 長谷部 茂, 中澤 敬信, 橋本 均, 松田 敏夫

日本薬理学雑誌   2017年02月

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研究論文（学術雑誌）

Regulation of emotional behaviors by juvenile environmental factors.

Kazuhiro Takuma, Yukio Ago, Shigeru Hasebe, Takanobu Nakazawa, Hitoshi Hashimoto, Toshio Matsuda

日本薬理学雑誌   2017年02月

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研究論文（学術雑誌）

Anti-anhedonic effect of selective serotonin reuptake inhibitors with affinity for sigma-1 receptors in picrotoxin-treated mice.

Shigeru Hasebe, Yukio Ago, Yuji Watabe, Satoshi Oka, 他6名

British Journal of Pharmacology   2017年01月

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研究論文（学術雑誌）

Role of Prefrontal Serotonergic and Dopaminergic Systems in Encounter-Induced Hyperactivity in Methamphetamine-Sensitized Mice.

Tatsunori Tanaka, Yukio Ago, Chiaki Umehara, Emina Imoto, Shigeru Hasebe, 他3名

International Journal of Neuropsychopharmacology   2016年12月

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研究論文（学術雑誌）

Involvement of GABAA receptors in 5-HT1A and σ1 receptor synergism on prefrontal dopaminergic transmission under circulating neurosteroid deficiency.

Yukio Ago, Shigeru Hasebe (equally contributed), Naoki Hiramatsu, Kazuya Mori, Yuji Watabe, 他4名

Psychopharmacology (Berl)   2016年06月

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研究論文（学術雑誌）

Prenatal Exposure to Histone Deacetylase Inhibitors Affects Gene Expression of Autism-Related Molecules and Delays Neuronal Maturation.

Takuya Kawanai, Yukio Ago, Ryo Watanabe, Aya Inoue, Atsuki Taruta, Yusuke Onaka, Shigeru Hasebe, 他3名

Neurochemical Research   2016年06月

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研究論文（学術雑誌）

The novel method female encounter test.

Yukio Ago, Shigeru Hasebe, Hitoshi Hashimoto, Kazuhiro Takuma, Toshio Matsuda

日本薬理学雑誌   2016年04月

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研究論文（学術雑誌）

Improvement by methylphenidate and atomoxetine of social interaction deficits and recognition memory impairment in a mouse model of valproic acid-induced autism.

Yuta Hara, Yukio Ago, Atsuki Taruta, Keisuke Katashiba, Shigeru Hasebe, 他4名

Autism Research   2015年12月

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研究論文（学術雑誌）

Rivastigmine improves isolation rearing-induced prepulse inhibition deficits via muscarinic acetylcholine receptors in mice.

Kosuke Higashino, Yukio Ago, Takahiro Umeki, Shigeru Hasebe, Yusuke Onaka, 他3名

Psychopharmacology (Berl)   2015年10月

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研究論文（学術雑誌）

Pharmacological profile of encounter-induced hyperactivity in isolation-reared mice.

Shigeru Hasebe, Yukio Ago, Saki Nishiyama, Satoshi Oka, Hitoshi Hashimoto, 他2名

Behavioral Pharmacology   2015年10月

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研究論文（学術雑誌）

Decreased expression of hippocampal Na⁺/Ca²⁺ exchanger isoform-1 by pentylenetetrazole kindling in mice.

Takuya Kawanai, Atsuki Taruta, Aya Inoue, Ryo Watanabe, Yukio Ago, Hitoshi Hashimoto, Shigeru Hasebe, 他3名

Epilepsy Research   2015年06月

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研究論文（学術雑誌）

The Female Encounter Test: A Novel Method for Evaluating Reward-Seeking Behavior or Motivation in Mice.

Yukio Ago, Shigeru Hasebe(equally contributed), Saki Nishiyama, Satoshi Oka, Yusuke Onaka, 他3名

International Journal of Neuropsychopharmacology   2015年05月

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研究論文（学術雑誌）

Anxiolytic-like effects of restraint during the dark cycle in adolescent mice.

Yuki Ota, Yukio Ago, Tatsunori Tanaka, Shigeru Hasebe, Yui Toratani, 他4名

Behavioral Brain Research   2015年02月

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研究論文（学術雑誌）

Role of the 5-HT1A autoreceptor in the enhancement of fluvoxamine-induced increases in prefrontal dopamine release by adrenalectomy/castration in mice.

Shigeru Hasebe, Naoki Hiramatsu, Yukio Ago, Kazuya Mori, Yuji Watabe 他3名

Journal of Pharmacological Sciences   2015年01月

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研究論文（学術雑誌）

Beneficial effect of cilostazol-mediated neuronal repair following trimethyltin-induced neuronal loss in the dentate gyrus.

Masanori Yoneyama, Masayuki Tanaka, Shigeru Hasebe, Taro Yamaguchi, Tatsuo Shiba, Kiyokazu Ogita

Journal of Neuroscience Research   2014年08月

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研究論文（学術雑誌）

Atomoxetine-induced increases in monoamine release in the prefrontal cortex are similar in spontaneously hypertensive rats and Wistar-Kyoto rats.

Yukio Ago, Masato Umehara, Kosuke Higashino, Shigeru Hasebe, Kazumi Fujita, 他2名

Neurochemical Research   2014年03月

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研究論文（学術雑誌）

Lithium promotes neuronal repair and ameliorates depression-like behavior following trimethyltin-induced neuronal loss in the dentate gyrus.

Masanori Yoneyama, Tatsuo Shiba, Shigeru Hasebe, Kasumi Umeda, Taro Yamaguchi, Kiyokazu Ogita

PLOS ONE   2014年02月

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研究論文（学術雑誌）

Involvement of prefrontal AMPA receptors in encounter stimulation-induced hyperactivity in isolation-reared mice.

Ryota Araki, Yukio Ago, Shigeru Hasebe, Saki Nishiyama, Tatsunori Tanaka, 他3名

International Journal of Neuropsychopharmacology   2014年01月

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研究論文（学術雑誌）

Beneficial in vivo effect of aripiprazole on neuronal regeneration following neuronal loss in the dentate gyrus: evaluation using a mouse model of trimethyltin-induced neuronal loss/self-repair in the dentate gyrus.

Masanori Yoneyama, Shigeru Hasebe, Noriko Kawamoto, Tatsuo Shiba, Taro Yamaguchi, Maho Kikuta, Makoto Shuto, Kiyokazu Ogita

Journal of Pharmacological Sciences   2013年12月

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研究論文（学術雑誌）

Isolation rearing reduces mechanical allodynia in a mouse model of chronic inflammatory pain.

Naotaka Horiguchi, Yukio Ago, Shigeru Hasebe, Kosuke Higashino, Kazuki Asada, 他3名

Pharmacology Biochemistry and Behavior   2013年10月

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研究論文（学術雑誌）

Synergistic effect of 5-HT1A and σ1 receptor activation on prefrontal dopaminergic transmission under circulating steroid deficiency.

Naoki Hiramatsu, Yukio Ago, Shigeru Hasebe, Akira Nishimura, Kazuya Mori, 他2名

Neuropharmacology   2013年07月

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研究論文（学術雑誌）

Activated microglial cells trigger neurogenesis following neuronal loss in the dentate gyrus of adult mice.

Kiyokazu Ogita, Masanori Yoneyama, Shigeru Hasebe, Tatsuo Shiba

日本神経精神薬理学雑誌   2012年11月

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研究論文（学術雑誌）

Indomethacin ameliorates trimethyltin-induced neuronal damage in vivo by attenuating oxidative stress in the dentate gyrus of mice.

Nguyen Quynh Huong, Yukary Nakamura, Nobuyuki Kuramoto, Masanori Yoneyama, Reiko Nagashima, Tatsuo Shiba, Taro Yamaguchi, Shigeru Hasebe, Kiyokazu Ogita

Biological and Pharmaceutical Bulletin   2011年09月

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研究論文（学術雑誌）