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Graduating School 【 display / non-display 】
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Setsunan University Faculty of Pharmaceutical Science 薬学科 Graduated
Degree 【 display / non-display 】
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Setsunan University - 学士（薬学）
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Setsunan University - Doctor (Pharmacy)
Academic Society Affiliations 【 display / non-display 】
- 日本薬剤学会
- 日本DDS学会
- 日本薬学会
Research field 【 display / non-display 】
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Life Science / Clinical pharmacy
Papers 【 display / non-display 】
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Impact of Composition of Lipid-Based Formulations on First-Pass Drug Metabolism after Oral Administration
Yusuke Tanaka, Rikuto Fukaishi, Daiki Okamoto, Takanori Kurakazu, Tokio Nakai, Haruya Yagi, Shinji Sakuma
Molecular Pharmaceutics22 2098 - 2107 2025.03
Joint Work
Research paper (scientific journal)
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The Improved Antigen Uptake and Presentation of Dendritic Cells Using Cell-Penetrating D-octaarginine-Linked PNVA-co-AA as a Novel Dendritic Cell-Based Vaccine
Yuri Fujioka, Hideto Ueki, Ruhan, Akari Sasajima, Takumi Tomono, Masami Ukawa, Haruya Yagi, Shinji Sakuma, Koichi Kitagawa, Toshiro Shirakawa
International Journal of Molecular Sciences25 2024.05
Joint Work
Research paper (scientific journal)
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In Vitro Digestion–In Situ Absorption Setup Employing a Physiologically Relevant Value of the Membrane Surface Area/Volume Ratio for Evaluating Performance of Lipid-Based Formulations: A Comparative Study with an In Vitro Digestion–Permeation Model
Yusuke Tanaka, Hinata Arai, Aya Hidaka, Saki Noda, Ko Imai, Fumiya Tsujisawa, Haruya Yagi, Shinji Sakuma
Molecular Pharmaceutics21 3459 - 3470 2024.05
Joint Work
Research paper (scientific journal)
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Validation of the absorption-enhancing ability of oligoarginines grafted onto a backbone of hyaluronic acid through animal studies from rodents to primates
Haruya Yagi, Takumi Tomono, Koji Abe, Yasuhiro Tsutsumi, Muneyoshi Makabe, Hiromi Mitsuhashi, Takayuki Kimura, Hideo Kobayashi, Kohei Miyata, Koichi Shigeno, Shinji Sakuma
Molecular Pharmaceutics21 3485 - 3501 2024.05
Joint Work
Research paper (scientific journal)
Authorship: Lead author
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Mucosal absorption of antibody drugs enhanced by cell-penetrating peptides anchored to a platform of polysaccharides
Takumi Tomono, Haruya Yagi, Ryoji Igi, Akihiro Tabaru, Koichi Fujimoto, Kaho Enomoto, Masami Ukawa, Kohei Miyata, Koichi Shigeno, Shinji Sakuma
International Journal of Pharmaceutics 2023.10
Joint Work
Research paper (scientific journal)
Review Papers 【 display / non-display 】
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Development of cell-penetrating peptide-linked polymers as tools that enhance transmucosal absorption of biologics
Haruya Yagi, Shinji Sakuma
The CELL Future medicinal chemistry explored by mid-size peptides 2023.07
Article, review, commentary, editorial, etc. (scientific journal) Joint Work
Authorship: Lead author
Presentations 【 display / non-display 】
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界面活性剤のP-糖タンパク質阻害活性に及ぼすリパーゼによる消化の影響
日本薬剤学会第40年会 Japan Domestic presentation Oral presentation (general)
2025.05 -
脂質製剤投与後の薬物経口吸収に及ぼすリパーゼ活性変動の影響
日本薬剤学会第40年会 Japan Domestic presentation Oral presentation (general)
2025.05 -
膜透過ペプチド固定化高分子を用いたmRNAのin vitro/in vivoトランスフェクション
日本薬剤学会第40年会 Japan Domestic presentation Oral presentation (general)
2025.05 -
バイオ医薬の取り込み促進能へ及ぼすオリゴアルギニン固定化ヒアルロン酸の構造特性の影響
日本薬剤学会第40年会 Japan Domestic presentation Oral presentation (general)
2025.05 -
膜透過ペプチド固定化高分子を用いた種々の抗体医薬の経鼻吸収促進
日本薬剤学会第40年会 Japan Domestic presentation Oral presentation (general)
2025.05
Industrial Property 【 display / non-display 】
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組成物、導入剤、RNAを、細胞内又は粘膜内に導入する方法
Patent
Application Number:2025-84428
佐久間信至、八木晴也、日渡謙一郎、福島一範、兜坂蛍、武藤美音
Application Date:2025.05.20
Awards 【 display / non-display 】
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第71回日本薬学会関西支部総会・大会 優秀ポスター賞
日本薬学会関西支部 Award from Japanese society, conference, symposium, etc.
Country:Japan
Research Grants and Projects 【 display / non-display 】
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膜透過ペプチド固定化高分子を用いた点眼投与による抗体医薬の眼内デリバリー
Grant number：25K18692 2025.04 - 2028.03
日本学術振興会 科学研究費助成事業 若手研究
Authorship：Principal investigator
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硝子体内注射に代わる抗体医薬の非侵襲的眼内送達システムの開発
2025.04 - 2026.03
日本私立学校振興・共済事業団 2025年度 若手・女性研究者奨励金
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Development of a novel hyaluronic acid-based delivery tool to improve the absorption of biologics
2024.04 - 2025.03
Iketani Science and Technology Foundation 単年度研究助成
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成長ホルモン分泌不全低身長症の非侵襲的治療を目指した口腔粘膜吸収促進技術の開発
2022.11 - 2023.03
成長科学協会 2022年度研究助成金【自由課題研究】