YAGI Haruya (YAGI Haruya)

写真a

Job title

Assistant Professor

External link

Graduating School 【 display / non-display

  • Setsunan University   Faculty of Pharmaceutical Science   薬学科  Graduated 

Degree 【 display / non-display

  • Setsunan University  -  学士(薬学)

  • Setsunan University  -  Doctor (Pharmacy)

Academic Society Affiliations 【 display / non-display

  • 日本薬剤学会
  • 日本DDS学会
  • 日本薬学会

Research field 【 display / non-display

  • Life Science / Clinical pharmacy

 

Papers 【 display / non-display

  • Impact of Composition of Lipid-Based Formulations on First-Pass Drug Metabolism after Oral Administration

    Yusuke Tanaka, Rikuto Fukaishi, Daiki Okamoto, Takanori Kurakazu, Tokio Nakai, Haruya Yagi, Shinji Sakuma

    Molecular Pharmaceutics22   2098 - 2107   2025.03

    Joint Work

    Research paper (scientific journal)

  • The Improved Antigen Uptake and Presentation of Dendritic Cells Using Cell-Penetrating D-octaarginine-Linked PNVA-co-AA as a Novel Dendritic Cell-Based Vaccine

    Yuri Fujioka, Hideto Ueki, Ruhan, Akari Sasajima, Takumi Tomono, Masami Ukawa, Haruya Yagi, Shinji Sakuma, Koichi Kitagawa, Toshiro Shirakawa

    International Journal of Molecular Sciences25   2024.05

    Joint Work

    Research paper (scientific journal)

  • In Vitro Digestion–In Situ Absorption Setup Employing a Physiologically Relevant Value of the Membrane Surface Area/Volume Ratio for Evaluating Performance of Lipid-Based Formulations: A Comparative Study with an In Vitro Digestion–Permeation Model

    Yusuke Tanaka, Hinata Arai, Aya Hidaka, Saki Noda, Ko Imai, Fumiya Tsujisawa, Haruya Yagi, Shinji Sakuma

    Molecular Pharmaceutics21   3459 - 3470   2024.05

    Joint Work

    Research paper (scientific journal)

  • Validation of the absorption-enhancing ability of oligoarginines grafted onto a backbone of hyaluronic acid through animal studies from rodents to primates

    Haruya Yagi, Takumi Tomono, Koji Abe, Yasuhiro Tsutsumi, Muneyoshi Makabe, Hiromi Mitsuhashi, Takayuki Kimura, Hideo Kobayashi, Kohei Miyata, Koichi Shigeno, Shinji Sakuma

    Molecular Pharmaceutics21   3485 - 3501   2024.05

    Joint Work

    Research paper (scientific journal)

    Authorship: Lead author 

  • Mucosal absorption of antibody drugs enhanced by cell-penetrating peptides anchored to a platform of polysaccharides

    Takumi Tomono, Haruya Yagi, Ryoji Igi, Akihiro Tabaru, Koichi Fujimoto, Kaho Enomoto, Masami Ukawa, Kohei Miyata, Koichi Shigeno, Shinji Sakuma

    International Journal of Pharmaceutics   2023.10

    Joint Work

    Research paper (scientific journal)

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Review Papers 【 display / non-display

  • Development of cell-penetrating peptide-linked polymers as tools that enhance transmucosal absorption of biologics

    Haruya Yagi, Shinji Sakuma

    The CELL Future medicinal chemistry explored by mid-size peptides    2023.07

    Article, review, commentary, editorial, etc. (scientific journal)  Joint Work

    Authorship: Lead author 

Presentations 【 display / non-display

  • バイオ医薬の経鼻吸収促進効果に及ぼすオリゴアルギニンを固定化したヒアルロン酸の分子量の影響

    日本薬学会第145年会  Japan  Domestic presentation  Oral presentation (general) 

    2025.03
     
     

  • Validation of the potential of oligoarginine-linked hyaluronic acid as an absorption enhancer through animal studies from rodents to primates

    American Association of Pharmaceutical Sciences PharmSci 360  Japan  International presentation  Poster presentation 

    2024.10
     
     

  • 消化管吸収促進剤としてのオリゴアルギニン固定化ビニルポリマーの有用性評価

    第40回日本DDS学会学術集会  Japan  Domestic presentation  Oral presentation (general) 

    2024.07
     
     

  • オリゴアルギニン固定化ヒアルロン酸のバイオ医薬に対する口腔粘膜吸収促進剤としての有用性評価

    第40回日本DDS学会学術集会  Japan  Domestic presentation  Oral presentation (general) 

    2024.07
     
     

  • 小腸表面積/水分量比を反映したin vitro消化-in situ吸収モデルによる脂質製剤からの薬物経口吸収性評価

    日本薬剤学会第39年会  Japan  Domestic presentation  Oral presentation (general) 

    2024.05
     
     

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Awards 【 display / non-display

  • 第71回日本薬学会関西支部総会・大会 優秀ポスター賞

    日本薬学会関西支部  Award from Japanese society, conference, symposium, etc. 

    Country:Japan

Research Grants and Projects 【 display / non-display

  • 膜透過ペプチド固定化高分子を用いた点眼投与による抗体医薬の眼内デリバリー

    Grant number:25K18692  2025.04 - 2028.03

    日本学術振興会   科学研究費助成事業 若手研究 

      More details

    Authorship:Principal investigator 

  • 硝子体内注射に代わる抗体医薬の非侵襲的眼内送達システムの開発

    2025.04 - 2026.03

    日本私立学校振興・共済事業団  2025年度 若手・女性研究者奨励金 

  • Development of a novel hyaluronic acid-based delivery tool to improve the absorption of biologics

    2024.04 - 2025.03

    Iketani Science and Technology Foundation  単年度研究助成 

  • 成長ホルモン分泌不全低身長症の非侵襲的治療を目指した口腔粘膜吸収促進技術の開発

    2022.11 - 2023.03

    成長科学協会  2022年度研究助成金【自由課題研究】