Papers - SAKUMA Shinji
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食後の吸収率低下の回避を目的とした新規製剤の開発：高pH溶解型腸溶性高分子の利用
丹野 史枝、小久保 宏恭、山下 伸二
Drug Delivery System25 ( 4 ) 384 - 391 2010.08
Joint Work
Research paper (scientific journal)
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Carboxyl group-terminated polyamidoamine dendrimers bearing glucosides inhibit intestinal hexose transporter-mediated D-glucose uptake.
Yumi Teraoka, Tomokazu Sagawa, et al.
Eur. J. Pharm. Biopharm.75 ( 3 ) 366 - 374 2010.08
Joint Work
Research paper (scientific journal)
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レクチン固定化蛍光ナノスフェアを用いた大腸がんの超早期診断法の開発
日渡 謙一郎、ロバート ホフマン、山下 伸二
Drug Delivery System25 ( 4 ) 403 - 410 2010.08
Joint Work
Research paper (scientific journal)
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Detection of early colorectal cancer imaged with peanut agglutinin-immobilized fluorescent nanospheres having surface poly(N-vinylacetamide) chains.
Takanori Yano, Yoshie Masaoka, et al.
Eur. J. Pharm. Biopharm.74 ( 3 ) 451 - 460 2010.03
Joint Work
Research paper (scientific journal)
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Mechanisms of membrane transport of poorly soluble drugs: role of micelles in oral absorption processes.
Koji Yano, Yoshie Masaoka, et al.
J. Pharm. Sci.99 ( 3 ) 1336 - 1345 2010.03
Joint Work
Research paper (scientific journal)
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Correlation between in vitro dissolution profiles from enteric-coated dosage forms and in vivo absorption in rats for high-solubility and high-permeability model drugs.
Ryoko Ogura, Yoshie Masaoka, et al.
J. Pharm. Sci.98 ( 11 ) 4141 - 4152 2009.11
Joint Work
Research paper (scientific journal)
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In vitro/in vivo biorecognition of lectin-immobilized fluorescent nanospheres for human colorectal cancer cells.
Takanori Yano, Yoshie Masaoka, et al.
J. Control. Release134 ( 1 ) 2月10日 2009.02
Joint Work
Research paper (scientific journal)
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Stabilization of enzyme-susceptible glucoside bonds of phloridzin through conjugation with poly(γ-glutamic acid).
Tomokazu Sagawa, Yoshie Masaoka, et al.
J. Control. Release133 ( 2 ) 125 - 131 2009.01
Joint Work
Research paper (scientific journal)
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Site-specific drug delivery to the middle-to-lower region of the small intestine reduces food-drug interactions that are responsible for low drug absorption in the fed state.
Fumie K. Tanno, Yoshie Masaoka, et al.
J. Pharm. Sci.97 ( 12 ) 5341 - 5353 2008.12
Joint Work
Research paper (scientific journal)
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Poly(N-vinylacetamide) chains enhance lectin-induced biorecognition through the reduction of nonspecific interactions with non-targets.
Ken-ichiro Hiwatari, Kiyoko Iwata, et al.
Eur. J. Pharm. Biopharm.70 ( 2 ) 453 - 461 2008.10
Joint Work
Research paper (scientific journal)
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Site-specific drug delivery to the middle region of the small intestine by application of enteric coating with hypromellose acetate succinate (HPMCAS).
Fumie K. Tanno, Yoshie Masaoka, et al.
J. Pharm. Sci.97 ( 7 ) 2665 - 2679 2008.07
Joint Work
Research paper (scientific journal)
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Scaling of in vitro membrane permeability to predict P-glycoprotein-mediated drug absorption in vivo.
Yoshiyuki Shirasaka, Yoshie Masaoka, et al.
Drug Metab. Dispo.36 ( 5 ) 916 - 922 2008.05
Joint Work
Research paper (scientific journal)
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Polymer-phloridzin conjugates as an anti-diabetic drug that inhibits glucose absorption through the Na+/glucose cotransporter (SGLT1) in the small intestine.
Yusuke Ikumi, Toshiyuki Kida, et al.
J. Control. Release125 ( 1 ) 42 - 49 2008.01
Joint Work
Research paper (scientific journal)
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Conjugation of poorly absorptive drugs with mucoadhesive polymers for the improvement of oral absorption of drugs.
Takaomi Matsumoto, Shinji Yamashita, et al.
J. Control. Release123 ( 3 ) 195 - 202 2007.11
Joint Work
Research paper (scientific journal)
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Effect of administration site in the gastrointestinal tract on bioavailability of poorly absorbed drugs taken after a meal.
Fumie K. Tanno, Yoshie Masaoka, et al.
J. Control. Release118 ( 1 ) 59 - 64 2006.12
Joint Work
Research paper (scientific journal)
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Site of drug absorption after oral administration: assessment of membrane permeability and luminal concentration of drugs in each segment of gastrointestinal tract.
Yoshie Masaoka, Yusuke Tanaka, et al.
Eur. J. Pharm. Sci.29 ( 3月4日 ) 240 - 250 2006.11
Joint Work
Research paper (scientific journal)
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Effect of food intake on the oral absorption of poorly water-soluble drugs: in vitro assessment of drug dissolution and permeation assay system.
Makoto Kataoka, Yoshie Masaoka, Shinji Yamashita
J. Pharm. Sci.95 ( 9 ) 2051 - 2061 2006.04
Joint Work
Research paper (scientific journal)