論文 - 木村 朋紀
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Partial contribution of the Keap1-Nrf2 system to cadmium-mediated metallothionein expression in vascular endothelial cells.
Yasuhiro Shinkai, Tomoki Kimura, Ayaka Itagaki, Chika Yamamoto, Keiko Taguchi, Masayuki Yamamoto, Yoshito Kumagai, Toshiyuki Kaji
Toxicology and Applied Pharmacology295 ( 1 ) 37 - 46 2016年03月
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研究論文(学術雑誌)
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The Functions of Metallothionein and ZIP and ZnT Transporters: An Overview and Perspective
Tomoki Kimura, Taiho Kambe
International Journal of Molecular Sciences17 ( 3 ) 336 2016年03月
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研究論文(学術雑誌)
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Chromium (VI)-induced transformation is enhanced by Zn deficiency in BALB/c 3T3 cells
Tomoki Kimura, Akira Onodera, Fumika Okumura, Tsuyoshi Nakanishi, Norio Itoh
The Journal of Toxicological Sciences40 ( 3 ) 383 - 387 2015年02月
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研究論文(学術雑誌)
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自己研鑚・参加型キャリア形成教育プログラム:「薬系インターンシップ・ボランティア体験実習」 -受講3年後の追跡調査から検証した体験実習の効果-
栗尾和佐子,小西元美,奥野智史,中尾晃幸,木村朋紀,辻琢己,山室晶子,山本祐実,西川智絵,柳田一夫,安原智久,河野武幸,荻田喜代一,曽根知道
薬学雑誌134 ( 11 ) 1199 - 1208 2014年07月
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研究論文(学術雑誌)
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Cooperative functions of ZnT1, metallothionein and ZnT4 in the cytoplasm are required for full activation of TNAP in the early secretory pathway
Shigeyuki Fujimoto , Naoya Itsumura , Tokuji Tsuji, Yasumi Anan, Natsuko Tsuji, Yasumitsu Ogra, Tomoki Kimura, Yusaku Miyamae, Seiji Masuda, Masaya Nagao, Taiho Kambe
PLoS One8 ( 10 ) e77445 2013年10月
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研究論文(学術雑誌)
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Bis(L-cysteinato)zincate(II) as a coordination compound that induces metallothionein gene transcription without inducing cell-stress-related gene transcription
Tomoki Kimura, Kengo Yoshida, Chika Yamamoto, Minako Suzuki, Tomoko Uno, Masakazu Isobe, Hiroshi Naka, Shuji Yasuike, Masahiko Satoh, Toshiyuki Kaji, Masanobu Uchiyama
Journal of Inorganic Biochemistry117 140 - 146 2012年12月
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研究論文(学術雑誌)
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Role of megalin and the soluble form of its ligand RAP in Cd-metallothionein endocytosis and Cd-metallothionein-induced nephrotoxicity in vivo
Akira Onodera, Miyuki Tani, Toshimi Michigami, Masayo Yamagata, Kyong-Son Min, Keiichi Tanaka, Tsuyoshi Nakanishi, Tomoki Kimura, Norio Itoh
Toxicology Letters212 91 - 96 2012年05月
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研究論文(学術雑誌)
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Possible aryl hydrocarbon receptor-independent pathway of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced antiproliferative response in human breast cancer cells.
Hiroki Yoshioka, Youhei Hiromori, Akira Aoki, Tomoki Kimura, Yoshiaki Fujii-Kuriyama, Hisamitsu Nagase, Tsuyoshi Nakanishi
Toxicology Letters211 ( 3 ) 257 - 265 2012年04月
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研究論文(学術雑誌)
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Chromium (VI) inhibits mouse metallothionein-I gene transcription by modifying the transcription potential of the co-activator p300
Tomoki Kimura, Fumika Okumura, Akira Onodera, Tsuyoshi Nakanishi, Norio Itoh, Masakazu Isobe
The Journal of Toxicological Sciences36 ( 2 ) 173 - 180 2011年04月
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研究論文(学術雑誌)
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Caspase-4 Directly Activates Caspase-9 in Endoplasmic Reticulum Stress-Induced Apoptosis in SH-SY5Y Cells
Akiko Yamamuro, Takashi Kishino, Yu Ohshima, Yasuhiro Yoshioka, Tomoki Kimura, Atsushi Kasai, Sadaaki Maeda
Journal of Pharmacological Sciences115 ( 2 ) 239 - 243 2011年01月
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研究論文(学術雑誌)
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The zinc-sensing transcription factor MTF-1 mediates zinc-induced epigenetic changes in chromatin of the mouse metallothionein-I promoter
Fumika Okumura, Yong Li, Norio Itoh, Tsuyoshi Nakanishi, Masakazu Isobe, Glen K.Andrews, Tomoki Kimura
Biochim Biophys Acta - Gene Regulatory Mechanisms1809 ( 1 ) 56 - 62 2011年01月
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研究論文(学術雑誌)
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Molecular mechanisms of zinc-mediated induction and chromium(VI)-mediated inhibition of mouse metallothionein-I gene transcription
Tomoki Kimura
Journal of Health Science56 ( 2 ) 161 - 166 2010年04月
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研究論文(学術雑誌)
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Mechanisms of heavy metal sensing by metal response element-binding transcription factor-1
Tomoki Kimura, Norio Itoh, Glen K. Andrews
Journal of Health Science55 484 - 494 2009年08月
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研究論文(学術雑誌)
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Ethanol-induced expression of glutamate-cysteine ligase catalytic subunit gene is mediated by NF-kappaB.
Tomoki Kimura, Yukiko Kawasaki, Fumika Okumura, Tomomichi Sone, Reiko Natsuki, Masakazu Isobe
Toxicology Letters185 110 - 115 2009年03月
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研究論文(学術雑誌)
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Metal response element-binding transcription factor-1 is activated by degradation of metallothionein.
Tomoki Kimura, Fumika Okumura, Ikuyo Oguro, Tsuyoshi Nakanishi, Tomomichi Sone, Masakazu Isobe, Keiichi Tanaka, Norio Itoh
Journal of Health Science55 72 - 76 2009年02月
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研究論文(学術雑誌)
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Chromium (VI) inhibits mouse metallothionein-I gene transcription by preventing the zinc-dependent formation of an MTF-1-p300 complex.
Tomoki Kimura, Yong Li, Fumika Okumura, Norio Itoh, Tsuyoshi Nakanishi, Tomomichi Sone, Masakazu Isobe, Glen K. Andrews
Biochemical Journal415 477 - 482 2008年11月
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研究論文(学術雑誌)
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Engineering expression of polyphosphate confers cadmium resistance in tobacco.
Takeshi Nagata, Tomoki Kimura, Hidemitsu Pan-Hou
Journal of Toxicological Sciences33 371 - 373 2008年08月
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研究論文(学術雑誌)
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Zinc-induced formation of a co-activator complex containing the zinc-sensing transcription factor MTF-1, p300/CBP and Sp1.
Yong Li, Tomoki Kimura, Ryan W. Huyck, John H. Laity, Glen K. Andrews
Molecular and Cellular Biology28 4275 - 4284 2008年07月
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研究論文(学術雑誌)
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Function of metallothionein in gene expression and signal transduction - Newly found protective role of metallothionein.
Tomoki Kimura, Norio Itoh
Journal of Health Science54 ( 3 ) 251 - 260 2008年03月
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研究論文(学術雑誌)
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Metallothionein induction by hypoxia involves cooperative interactions between MTF-1 and HIF-1alpha.
Brian J. Murphy, Tomoki Kimura, Barbara G. Sato, Yihui Shi and Glen K. Andrews
Molecular Cancer Research6 483 - 490 2008年03月
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研究論文(学術雑誌)