YOSHIOKA Yasuhiro (YOSHIOKA Yasuhiro)

写真a

Job title

Professor

Homepage URL

http://www.setsunan.ac.jp/

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Graduating School 【 display / non-display 】

  • Osaka University   Faculty of Pharmaceutical Science   薬学科  Graduated 

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Graduate School 【 display / non-display 】

  • Osaka University   Graduate School, Division of Pharmaceutical Sciences   応用医療薬科学専攻  Master's Course  Completed 

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Degree 【 display / non-display 】

  • Osaka University  -  薬学士

  • Osaka University  -  博士（薬学）

  • Osaka University  -  Master (Pharmaceutical Sciences)

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Academic Society Affiliations 【 display / non-display 】

  • 日本薬学会
  • 日本薬理学会
  • 日本神経化学会
  • 日本生化学会
  • 米国神経科学会

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Research field 【 display / non-display 】

  • Life Science / Pharmaceutical hygiene and biochemistry

  • Life Science / Neuroscience-general  (Pharmacology,Neuropharmacology,Pharmacotherapy)

  • Life Science / Pharmacology  (薬物治療学、神経薬理学)

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Research Career 【 display / non-display 】

  • グリア細胞を介した神経細胞保護作用に関する研究

    Classification of research:Collaboration in Organization 

    Project Year:2007

    Keyword:アストロサイト、ミクログリア

  • Mechanisms of cytoprotection by nitric oxide

    Classification of research:Collaboration in Organization 

    Project Year:

    Keyword:Nitric oxide, cytoprotection

  • Mechanisms of cell injury by nitric oxide.

    Classification of research:Collaboration in Organization 

    Project Year:

    Keyword:Nitric oxide,cell injury.

  • Correlation of tyrosine phosphorylation and cell death.

    Classification of research:Collaboration in Organization 

    Project Year:

    Keyword:Tyrosine phosphorylation,cell death

  • 一酸化窒素による細胞保護機構

    Classification of research:Collaboration in Organization 

    Project Year:

    Keyword:一酸化窒素

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Papers 【 display / non-display 】

  • L-Theanine Uptake via Solute Carrier Family 38 Member 1 Inhibits Neuroblastoma Cell Growth

    Koichi Kawada, Yuri Matsushima, Ruka Nakamura, Megumi Nishio, Yuka Watanabe, Shuhei Araki, Tamika Sudo, Sayuki Yoshikawa, Mitsuhiro Shibata, Toshihiko Kinjo, Kyosuke Uno, Yutaro Higashiura, Akiko Yamamuro, Yuki Ishimaru, Yasuhiro Yoshioka, Sadaaki Maeda & Nobuyuki Kuramoto

    Neurochem Res.51 ( 1 ) 17   2025.12

    Joint Work

    Research paper (scientific journal)

    DOI

  • Proteasome inhibitors induce apoptosis by superoxide anion generation via NADPH oxidase 5 in human neuroblastoma SH-SY5Y cells.

    Akiko Yamamuro-Tanabe, Yu Oshima, Takumi Iyama, Yuki Ishimaru, and Yasuhiro Yoshioka

    J Pharmacol Sci.155 ( 2 ) 52 - 62   2024.06

    Joint Work

    Research paper (scientific journal)

    Authorship: Last author  Corresponding author

  • An Increase in Peroxiredoxin 6 Expression Induces Neurotoxic A1 Astrocytes in the Lumbar Spinal Cord of Amyotrophic Lateral Sclerosis Mice Model.

    Yamamuro-Tanabe A, Mukai Y, Kojima W, Zheng S, Matsumoto N, Takada S, Mizuhara M, Kosuge Y, Ishimaru Y, Yoshioka Y.

    Neurochem Res.48 ( 12 ) 3571 - 3584   2023.12

    Joint Work

    Research paper (scientific journal)

    Authorship: Corresponding author

  • Schwann cell derived-peroxiredoxin protects motor neurons against hydrogen peroxide-induced cell death in mouse motor neuron cell line NSC-34

    Yamamuro-Tanabe A, Kosuge Y, Ishimaru Y, Yoshioka Y.

    J Pharmacol Sci.153 ( 2 ) 73 - 83   2023.10

    Joint Work

    Research paper (scientific journal)

    Authorship: Corresponding author

  • Dopamine inhibits the expression of proinflammatory cytokines of microglial cells through the formation of dopamine quinone in the mouse striatum

    Yasuhiro Yoshioka, Yuta Sugino, Akiko Yamamuro, Yuki Ishimaru, Sadaaki Maeda

    Journal of Pharmacological Sciences148 ( 1 ) 41 - 50   2021.10

    Joint Work

    Research paper (scientific journal)

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Books 【 display / non-display 】

  • 内分泌疾患　代謝疾患

    井口智恵，稲野寛，井上岳，野島浩幸，吉岡靖啓Other  Joint author

    オーム社  2018.09

  • 循環器疾患・救急医療　血液疾患

    小松敏彰，岩澤真紀子，久保田理恵，近藤留美子，吉岡靖啓Other  Joint author

    オーム社  2017.06

  • Degenaration and Regenaration in Neurons, 2006: 109-123

    吉岡　靖啓Scholarly book  Other

    Research Signpost  2006

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Review Papers 【 display / non-display 】

  • マクロファージにおける一酸化窒素による細胞死制御機構に関する薬理学的研究

    吉岡　靖啓

    ( 大阪大学 )   2006.08

    Other  Single Work

  • 癌抑制遺伝子p53による老化の制御

    吉岡靖啓, 前田定秋

    日本薬理学雑誌   121 ( 2 ) 130  2003.02

    Other  Joint Work

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Presentations 【 display / non-display 】

  • The induction of neurotoxic reactive astrocyte phenotype in cultured astrocyte.

    日本薬学会第146年会  大阪  Japan  Domestic presentation  Oral presentation (general) 

    2026.03
    　
    　

    Announcement date:2026.03.27

  • The apelin–APJ system attenuates retinal ganglion cell death induced by retinal ischemia–reperfusion in mice

    第99回日本薬理学会年会  仙台  Japan 

    2026.03
    　
    　

    Announcement date:2026.03.18

  • Protective effect of intermittent fasting on retinal neurodegeneration in diabetic model mice.

    第99回日本薬理学会年会  仙台  Japan  Poster presentation 

    2026.03
    　
    　

  • Overexpression of SOD1 G93A in cultured astrocytes promotes the induction of neurotoxic reactive astrocyte-like phenotypes.

    第29回グリア研究会  仙台  Japan  Domestic presentation  Oral presentation (invited, special) 

    2025.12
    　
    　

  • 糖尿病モデルマウスにおける断続的断食による網膜神経障害抑制作用

    次世代を担う若手のための創薬・医療薬理シンポジウム2025  仙台  Japan  Oral presentation (general) 

    2025.08
    　
    　

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Industrial Property 【 display / non-display 】

  • 網膜神経保護作用を有するアペリン受容体アゴニストを含有する医薬組成物

    Patent

    Application Number:特願2018-192861 

    石丸侑希，前田定秋， 吉岡靖啓

    Application Date:2018.10.11  Applicant:学校法人常翔学園

    Country of applicant: Domestic 

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