KONISHI Motomi (KONISHI Motomi)

写真a

Job title

Professor

Homepage URL

http://www.setsunan.ac.jp/

Research Interests 【 display / non-display

  • 天然物化学

  • 分析科学

  • 物理系薬学

Graduating School 【 display / non-display

  • Kobe Pharmaceutical University   Faculty of Pharmaceutical Science   衛生薬学科  Graduated 

Graduate School 【 display / non-display

  • Kobe Pharmaceutical University   Graduate School, Division of Pharmaceutical Sciences   Master's Course  Completed 

Degree 【 display / non-display

  • Kobe Pharmaceutical University  -  薬学士

  • Kobe Pharmaceutical University  -  修士

  • Kanazawa University  -  博士(薬学)

Academic Society Affiliations 【 display / non-display

  • 日本生薬学会
  • 日本生化学会
  • 日本分析化学会
  • 日本薬学会

Research field 【 display / non-display

  • Life Science / Pharmaceutical analytical chemistry and physicochemistry

 

Research Career 【 display / non-display

  • アミロイドβを加水分解するペプチドの立体構造解析

    Project Year:2014.04  -  Now 

    Keyword:加水分解酵素、アミロイドβ、ペプチド

  • Search for Matrix Metalloproteinase Inhibitors

    Classification of research:Collaboration in Organization 

    Project Year:

    Keyword:MMP, Inhibitor

  • 動植物中の抗転移物質の構造解析

    Project Year:

  • Studies on Cardiac Steroids

    Project Year:

    Keyword:Bufadienolide,Na+,K+-ATPase

  • 抗転移物質の検索

    Project Year:

Papers 【 display / non-display

  • SKGQA, a Peptide Derived from the ANA/BTG3 Protein, Cleaves Amyloid-β with Proteolytic Activity

    Yusuke Hatakawa, Rina Nakamura, Toshifumi Akizawa, Motomi Konishi, Akira Matsuda, Tomoyuki Oe, Motoaki Saito, Fumiaki Ito

    Biomolecules14 ( 5 )   586   2024.05

    Joint Work

    Research paper (scientific journal)

    DOI

  • Five-mer peptides prevent short-term spatial memory defcits in Aβ25-35-induced Alzheimer’s model mouse by suppressing Aβ25-35 aggregation and resolving its aggregate form

    Rina Nakamura, Motomi Konishi , Youichirou Higashi , Motoaki Saito, Toshifumi Akizawa

    Alzheimer’s Research & Therapy 15   83   2023.04

    Joint Work

    Research paper (scientific journal)

    DOI

  • Structure–Activity Relationship of 5-mer Catalytides, GSGYR and RYGSG

    Rina Nakamura; Toshifumi Akizawa; Motomi Konishi

    Biomolecules12 ( 12 )   2022.11

    Joint Work

    Research paper (scientific journal)

    DOI

  • Direct Delivery of ANA-TA9, a Peptide Capable of Aβ Hydrolysis, to the Brain by Intranasal Administration

    Yusuke Hatakawa, Akiko Tanaka, Tomoyuki Furubayashi, Rina Nakamura, Motomi Konishi, Toshifumi Akizawa, Toshiyasu Sanane,,

    Pharmaceutics13 ( 10 )   pharmaceutics13101673   2021.10

    Joint Work

    Research paper (scientific journal)

    DOI

  • Amyloid-beta cleavage by ANA-TA9, a synthetic peptide from the ANA/BTG3 Box A region

    Yusuke Hatakawa, Rina Nakamura, Motomi Konishi, Toshiyasu Sanane, Akiko Tanaka, Akira Matsuda, Motoaki Saito, Toshifumi Akizawa

    Alzheimers Dement (N Y)7 ( 1 )   e12146   2021.03

    Joint Work

    Research paper (scientific journal)

    DOI

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Books 【 display / non-display

  • 「薬学テキストシリーズ」 分析化学Ⅰ 定量分析編 第2版

    中込和哉、秋澤俊史、小西元美、小林茂樹、西宮一総、馬渡健一 (Part : 1章、4章)  Textbook, survey, introduction  Joint author

    朝倉書店  2018.04

  • 薬剤師に必要な臨床機器分析

    秋澤俊史、川原正博、小谷明、谷本剛、袴田秀樹、道田隆 (Part : 第5章 MS)  Scholarly book  Joint author

    廣川書店  2010.08

Presentations 【 display / non-display

  • Possibility of short synthetic peptides with activities of suppressing amyloid b aggregation and resolving its aggregated form as therapeutic drugs for Alzheimer's disease

    The 97th Annual Meeting of the Japanease Pharmacological Society  KOBE CONBENTION CENTER  Domestic presentation  Oral presentation (general) 

    2023.12
     
     

    Announcement date:2023.12.14

    [Proceedings] 第97回日本薬理学会年会 講演要旨集  2023.12

  • Delivery of JAL-TA9 to the brain by nasal application

    The 97th Annual Meeting of the Japanease Pharmacological Society  KOBE CONBENTION CENTER  Japan  Domestic presentation  Oral presentation (general) 

    2023.12
     
     

    Announcement date:2023.12.14

    [Proceedings] 第97回日本薬理学会年会 講演要旨集  2023.12

  • Effects of JAL-TA9 on cognitive deficits in Alzheimer's disease model mouse

    The 97th Annual Meeting of the Japanease Pharmacological Society  KOBE CONBENTION CENTER  Domestic presentation  Oral presentation (general) 

    2023.12
     
     

    Announcement date:2023.12.14

    [Proceedings] 第97回日本薬理学会年会 講演要旨集  2023.12

  • The discovery of JAL-TA9 which cleaves amyloid-β with proteolytic activity

    The 97th Annual Meeting of the Japanease Pharmacological Society  KOBE CONBENTION CENTER  Domestic presentation  Oral presentation (general) 

    2023.12
     
     

    Announcement date:2023.07.28

    [Proceedings] 第97回日本薬理学会年会 講演要旨集  2023.12

  • Docking simulation of 5-Mer Peptide GSGFK and Aβ25-35

    73st Kansai Regional Meeting of the Pharmaceutical Society of Japan  KOBE GAKUIN Univ.  Domestic presentation  Poster presentation 

    2023.10
     
     

    Announcement date:2023.10.14

    [Proceedings] 73st Kansai Regional Meeting of the Pharmaceutical Society of Japan  51  -  51  2023.09

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Other research activities 【 display / non-display

  • Studies on Cardiac Steroids

    Other 

    1990