ISHIMARU Yuki (ISHIMARU Yuki)

写真a

Job title

Assistant Professor

Graduating School 【 display / non-display

  • Setsunan University  Faculty of Pharmaceutical Science  Graduated 

Graduate School 【 display / non-display

  • Setsunan University  Graduate School, Division of Pharmaceutical Sciences  Pharmaceutical science  Master's Course  Completed

Academic Society Affiliations 【 display / non-display

  • The Japanese Pharmacological Society
  • The Pharmaceutical Society of Japan
  • The Japanese Society for Neurochemistry
  • The Japanese Biochemical Society
  • Japanese Journal of Ocular Pharmacology

Research field 【 display / non-display

  • Pharmacology in pharmacy (Vascular biology, Neuropharmacology)

 

Papers 【 display / non-display

  • An apelin receptor antagonist prevents pathological retinal angiogenesis with ischemic retinopathy in mice

    Yuki Ishimaru, Fumiya Shibagaki, Akiko Yamamuro, Yasuhiro Yoshioka & Sadaaki Maeda

    Scientific Reports7 ( 1 ) 15062   2017.11

    Joint Work

    Research paper (scientific journal)

    DOI

  • Apelin protects against NMDA-induced retinal neuronal death via an APJ receptor by activating Akt and ERK1/2, and suppressing TNF-α expression in mice.

    Ishimaru Y, Sumino A, Kajioka D, Shibagaki F, Yamamuro A, Yoshioka Y, Maeda S.

    J Pharmacol Sci.133 ( 1 ) 34 - 41   2017.01

    Joint Work

    Research paper (scientific journal)

    DOI

  • Noradrenaline increases intracellular glutathione in human astrocytoma U-251 MG cells by inducing glutamate-cysteine ligase protein via β3-adrenoceptor stimulation.

    Yoshioka Y, Kadoi H, Yamamuro A, Ishimaru Y, Maeda S.

    Eur J Pharmacol.772   51 - 61   2016.02

    Joint Work

    Research paper (scientific journal)

  • Dopamine inhibits lipopolysaccharide-induced nitric oxide production through the formation of dopamine quinone in murine microglia BV-2 cells.

    Yoshioka Y, Sugino Y, Tozawa A, Yamamuro A, Kasai A, Ishimaru Y, Maeda S.

    J Pharmacol Sci.130 ( 2 ) 51 - 59   2016.02

    Joint Work

    Research paper (scientific journal)

  • Potential of D-Octaarginine-Linked Polymers as an in Vitro Transfection Tool for Biomolecules.

    Kohta Mohri, Naoki Morimoto, Megumi Maruyama, Norimasa Nakamoto, Emi Hayashi, Kengo Nagata, Kohei Miyata, Kyohei Ochiai, Ken-ichiro Hiwatari, Kazufumi Tsubaki, Etsuo Tobita, Yuki Ishimaru, Sadaaki Maeda, and Shinji Sakuma.

    Bioconjugate Chemistry26 ( 8 ) 1782 - 1790   2015.08

    Joint Work

    Research paper (scientific journal)

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Presentations 【 display / non-display

  • Protective effect of an apelin receptor agonist on retinal ganglion cell death induced by retinal ischemia-reperfusion injury in mice

    18th World Congress of Basic and Clinical Pharmacology  国立京都国際会館  International conference  Poster (general) 

    2018.07
     
     

  • An apelin receptor antagonist inhibits pathological retinal angiogenesis in a mouse model of ischemic retinopathy

    18th World Congress of Basic and Clinical Pharmacology  国立京都国際会館  International conference  Poster (general) 

    2018.07
     
     

  • Noradrenaline protect motor neurons from hydrogen peroxide-induced cell death by increasing the supply of GSH from astrocytes via β3-adrenoreceptor stimulation

    18th World Congress of Basic and Clinical Pharmacology  国立京都国際会館  International conference  Poster (general) 

    2018.07
     
     

  • Apelin inhibits N-methyl-D-aspartate-induced retinal ganglion cell death by activating AKT and ERK via APJ receptor in mice

    2017 ISN-ESN meeting  International conference  Poster (general) 

    2017.08
     
     

  • Dopamine attenuates LPS-induced cytokine expression by inhibiting the nuclear translocation of nf-kb p65 in microglial BV-2 cells

    2017 ISN-ESN meeting  International conference  Poster (general) 

    2017.08
     
     

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Other research activities 【 display / non-display

  • Apelin/APJ system as a novel therapeutic target in ischemic retinopathy

    Other 

    2013.08
     
     

    Japan Science and Technology Agency