ISHIMARU Yuki (ISHIMARU Yuki)

写真a

Job title

Assistant Professor

Graduating School 【 display / non-display

  • Setsunan University  Faculty of Pharmaceutical Science  Graduated 

Graduate School 【 display / non-display

  • Setsunan University  Graduate School, Division of Pharmaceutical Sciences  Pharmaceutical science  Master's Course  Completed

Academic Society Affiliations 【 display / non-display

  • The Japanese Pharmacological Society
  • The Pharmaceutical Society of Japan
  • The Japanese Society for Neurochemistry
  • Japanese Journal of Ocular Pharmacology
  • International Society for Neurochemistry

Research field 【 display / non-display

  • Pharmacology in pharmacy (Vascular biology, Neuropharmacology)

 

Papers 【 display / non-display

  • Endogenous Apelin Is Protective Against Age-Associated Loss of Retinal Ganglion Cells in Mice

    Yuki Ishimaru, Akihide Sumino, Fumiya Shibagaki, Akiko Yamamuro, Yasuhiro Yoshioka, Sadaaki Maeda

    Frontiers in Aging Neuroscience12   58   2020.03

    Joint Work

    Research paper (scientific journal)

    DOI

  • Systemic Administration of an Apelin Receptor Agonist Prevents NMDA-Induced Loss of Retinal Neuronal Cells in Mice

    Fumiya Shibagaki, Yuki Ishimaru, Akihide Sumino, Akiko Yamamuro, Yasuhiro Yoshioka, Sadaaki Maeda

    Neurochemical Research45   752 - 759   2020.01

    Joint Work

    Research paper (scientific journal)

    DOI

  • Dopamine attenuates lipopolysaccharide-induced expression of proinflammatory cytokines by inhibiting the nuclear translocation of NF-κB p65 through the formation of dopamine quinone in microglia.

    Yasuhiro Yoshioka, Yuta Sugino, Fumiya Shibagaki, Akiko Yamamuro, Yuki Ishimaru, Sadaaki Maeda

    European Journal of Pharmacology866   172826   2019.11

    Joint Work

    Research paper (scientific journal)

    DOI

  • An apelin receptor antagonist prevents pathological retinal angiogenesis with ischemic retinopathy in mice

    Yuki Ishimaru, Fumiya Shibagaki, Akiko Yamamuro, Yasuhiro Yoshioka, Sadaaki Maeda

    Scientific Reports7 ( 1 ) 15062   2017.11

    Joint Work

    Research paper (scientific journal)

    DOI

  • Apelin protects against NMDA-induced retinal neuronal death via an APJ receptor by activating Akt and ERK1/2, and suppressing TNF-α expression in mice.

    Yuki Ishimaru, Akihide Sumino, Daiki Kajioka, Fumiya Shibagaki, Akiko Yamamuro, Yasuhiro Yoshioka, Sadaaki Maeda

    Journal of Pharmacological Sciences133 ( 1 ) 34 - 41   2017.01

    Joint Work

    Research paper (scientific journal)

    DOI

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Presentations 【 display / non-display

  • DA attenuates LPS-induced cytokine expression by inhibiting the microtubule-dependent nuclear transport of NF-KB P65 in BV-2 cells

    2019 ISN-ASN meeting  Montreal  International conference  Poster (general) 

    2019.08
     
     

  • Neuroprotective effect of the endogenous peptide apelin on the retinal ganglion cell death in diabetes model mouse

    2019 ISN-ASN meeting  Montreal  International conference  Poster (general) 

    2019.08
     
     

  • An apelin receptor agonist protects against retinal neuronal cell death induced by N-methyl-D-aspartic acid in mice

    2019 ISN-ASN meeting  Montreal  International conference  Poster (general) 

    2019.08
     
     

  • L-theanine inhibits the proliferation of neural cell lines via an L-glutamine transporter SLC38A1

    2019 ISN-ASN meeting  Montreal  International conference  Poster (general) 

    2019.08
     
     

  • Protective effect of an apelin receptor agonist on retinal ganglion cell death induced by retinal ischemia-reperfusion injury in mice

    18th World Congress of Basic and Clinical Pharmacology  国立京都国際会館  International conference  Poster (general) 

    2018.07
     
     

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Other research activities 【 display / non-display

  • Apelin/APJ system as a novel therapeutic target in ischemic retinopathy

    Other 

    2013.08
     
     

    Japan Science and Technology Agency