MAEDA Sadaaki (MAEDA Sadaaki)

写真a

Job title

Professor

Graduating School 【 display / non-display

  • Osaka University  Faculty of Pharmaceutical Science  Graduated 

Graduate School 【 display / non-display

  • Osaka University  Graduate School, Division of Pharmaceutical Sciences  Doctor's Course  Accomplished credits for doctoral program

Research field 【 display / non-display

  • Neurochemistry/Neuropharmacology (Pharmacology,Neuropharmacology,Pharmacotherapy)

  • Biological pharmacy

  • General pharmacology

 

Research Career 【 display / non-display

  • apelin/APJ system in the spinal cord has a neuroprotective effect against the pathogenesis of Amyotrophic lateral sclerosis.

    Classification of research:Collaboration in Organization 

    Project Year:2009

    Keyword:Amyotrophic lateral sclerosis(ALS), apelin, APJ

  • Molecular pharmacological study on physiological function of apelin in angiogenesis

    Classification of research:Collaboration in Organization 

    Project Year:2007

    Keyword:apelin, angiogenesis, neuronal cells

Papers 【 display / non-display

  • An apelin receptor antagonist prevents pathological retinal angiogenesis with ischemic retinopathy in mice.

    Ishimaru Y., Shibagaki F., Yamamuro A., Yoshioka Y., Maeda S.

    Scientific Reports7 ( 1 ) 15062   2017.11

    Joint Work

    Research paper (scientific journal)

    DOI

  • Apelin protects against NMDA-induced retinal neuronal death via an APJ receptor by activating Akt and ERK1/2, and suppressing TNF-α expression in mice.

    Ishimaru Y, Sumino A, Kajioka D, Shibagaki F, Yamamuro A, Yoshioka Y, Maeda S.

    J Pharmacol Sci. 133 ( 1 ) 34 - 41   2017.01

    Joint Work

    Research paper (scientific journal)

  • マウスミクログリア株BV-2細胞におけるドパミンによるリポポリサッカライドにより誘導される一酸化窒素産生の抑制

    吉岡靖啓、杉野佑太、戸澤梓、山室晶子、笠井淳司、石丸侑希、前田定秋

    J Pharmacol Sci.130 ( 2 ) 51 - 59   2016.02

    Joint Work

    Research paper (scientific journal)

  • ヒトアストロサイトーマU251-MG細胞におけるノルアドレナリンによるβ3受容体を介したグルタミン酸-システイン リガーゼの発現を介した細胞内グルタチオンの増加作用

    吉岡靖啓、門居久嗣、石丸侑希、山室晶子、前田定秋

    Eur J Pharmacol.772   51 - 61   2016.02

    Joint Work

    Research paper (scientific journal)

  • Apelin protects against loss of retinal ganglion cells in a glaucoma model mouse

    Ishimaru Y, Sumino A, Maeda S.

    772   41 - 43   2015.08

    Joint Work

    Research paper (scientific journal)

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Books 【 display / non-display

  • Diseases and Pharmacotherapy Gastrointestinal disease

    Akihiko itoh, Keiko Ohno et.alTextbook  Joint Editor

    ohmusha  2017.03

Presentations 【 display / non-display

  • An apelin receptor antagonist inhibits pathological retinal angiogenesis in a mouse model of ischemic retinopathy

    第18回国際薬理学・臨床薬理学会議(WCP2018)  京都  International conference  Poster (general) 

    2018.07
     
     

  • Pharmacological investigation of the role of aplnr and its post-translational modification

    第18回国際薬理学・臨床薬理学会議(WCP2018)  京都  International conference  Poster (general) 

    2018.07
     
     

  • Protective effect of an apelin receptor agonist on retinal ganglion cell death induced by retinal ischemia-reperfusion injury in mice

    第18回国際薬理学・臨床薬理学会議(WCP2018)  京都  International conference  Poster (general) 

    2018.07
     
     

  • Noradrenaline protect motor neurons from hydrogen peroxide-induced cell death by increasing the supply of GSH from astrocytes via β3-adrenoreceptor stimulation

    第18回国際薬理学・臨床薬理学会議(WCP2018)  京都  International conference  Poster (general) 

    2018.07
     
     

  • Dopamine attenuates LPS-induced cytokine expression by inhibiting the nuclear translocation of nf-kb p65 in microglial BV-2 cells

    2017 ISN-ESN meeting  Paris  International conference  Poster (general) 

    2017.08
     
     

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