MAEDA Sadaaki (MAEDA Sadaaki)

写真a

Job title

Vice President

Graduating School 【 display / non-display

  • Osaka University  Faculty of Pharmaceutical Science  Graduated 

Graduate School 【 display / non-display

  • Osaka University  Graduate School, Division of Pharmaceutical Sciences  Doctor's Course  Accomplished credits for doctoral program

Research field 【 display / non-display

  • Neurochemistry/Neuropharmacology (Pharmacology,Neuropharmacology,Pharmacotherapy)

  • Biological pharmacy

  • General pharmacology

 

Research Career 【 display / non-display

  • apelin/APJ system in the spinal cord has a neuroprotective effect against the pathogenesis of Amyotrophic lateral sclerosis.

    Classification of research:Collaboration in Organization 

    Project Year:2009

    Keyword:Amyotrophic lateral sclerosis(ALS), apelin, APJ

  • Molecular pharmacological study on physiological function of apelin in angiogenesis

    Classification of research:Collaboration in Organization 

    Project Year:2007

    Keyword:apelin, angiogenesis, neuronal cells

Papers 【 display / non-display

  • Endogenous Apelin Is Protective Against Age-Associated Loss of Retinal Ganglion Cells in Mice

    Yuki Ishimaru, Akihide Sumino, Fumiya Shibagaki, Akiko Yamamuro, Yasuhiro Yoshioka, Sadaaki Maeda

    Frontiers in Aging Neuroscience12   58   2020.03

    Joint Work

    Research paper (scientific journal)

    DOI

  • Systemic Administration of an Apelin Receptor Agonist Prevents NMDA-Induced Loss of Retinal Neuronal Cells in Mice

    Fumiya Shibagaki, Yuki Ishimaru, Akihide Sumino, Akiko Yamamuro, Yasuhiro Yoshioka, Sadaaki Maeda

    Neurochemical Research45   752 - 759   2020.01

    Joint Work

    Research paper (scientific journal)

    DOI

  • Dopamine attenuates lipopolysaccharide-induced expression of proinflammatory cytokines by inhibiting the nuclear translocation of NF-κB p65 through the formation of dopamine quinone in microglia.

    Yasuhiro Yoshioka, Yuta Sugino, Fumiya Shibagaki, Akiko Yamamuro, Yuki Ishimaru, Sadaaki Maeda

    European Journal of Pharmacology866   172826   2019.11

    Joint Work

    Research paper (scientific journal)

    DOI

  • An apelin receptor antagonist prevents pathological retinal angiogenesis with ischemic retinopathy in mice.

    Ishimaru Y., Shibagaki F., Yamamuro A., Yoshioka Y., Maeda S.

    Scientific Reports7 ( 1 ) 15062   2017.11

    Joint Work

    Research paper (scientific journal)

    DOI

  • Apelin protects against NMDA-induced retinal neuronal death via an APJ receptor by activating Akt and ERK1/2, and suppressing TNF-α expression in mice.

    Ishimaru Y, Sumino A, Kajioka D, Shibagaki F, Yamamuro A, Yoshioka Y, Maeda S.

    J Pharmacol Sci. 133 ( 1 ) 34 - 41   2017.01

    Joint Work

    Research paper (scientific journal)

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Books 【 display / non-display

  • Diseases and Pharmacotherapy Gastrointestinal disease

    Akihiko itoh, Keiko Ohno et.alTextbook  Joint Editor

    ohmusha  2017.03

Presentations 【 display / non-display

  • L-theanine inhibits the proliferation of neural cell lines via an L-glutamine transporter SLC38A1

    2019 ISN-ASN meeting  Montreal  International conference  Poster (general) 

    2019.08
     
     

  • An apelin receptor agonist protects against retinal neuronal cell death induced by N-methyl-D-aspartic acid in mice

    2019 ISN-ASN meeting  Montreal  International conference  Poster (general) 

    2019.08
     
     

  • Neuroprotective effect of the endogenous peptide apelin on the retinal ganglion cell death in diabetes model mouse

    2019 ISN-ASN meeting  Montreal  International conference  Poster (general) 

    2019.08
     
     

  • DA attenuates LPS-induced cytokine expression by inhibiting the microtubule-dependent nuclear transport of NF-KB P65 in BV-2 cells

    2019 ISN-ASN meeting  Montreal  International conference  Poster (general) 

    2019.08
     
     

  • Exploring the role of post translational modifications for APLNR in the mouse central nervous system

    2019 ISN-ASN meeting  Montreal  International conference  Poster (general) 

    2019.08
     
     

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